(Q52659046)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25859013%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25859013%20AND%20SRC:MED&resulttype=core&format=json

amyotrophic lateral sclerosis

5 March 2020

main subject

0 references

author

Adam Walker

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25859013%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Jennifer A. Fifita

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25859013%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Kelly L Williams

6

1 reference

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5 March 2020

Gilles J. Guillemin

8

1 reference

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5 March 2020

Vinod Sundaramoorthy

1

1 reference

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5 March 2020

Vanessa Tan

3

1 reference

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5 March 2020

Ian P Blair

7

1 reference

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5 March 2020

Julie D Atkin

10

1 reference

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5 March 2020

9

Manal A Farg

1 reference

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5 March 2020

author name string

Emily P Mccann

5

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5 March 2020

publication date

9 April 2015

1 reference

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5 March 2020

published in

Human Molecular Genetics

1 reference

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5 March 2020

volume

24

1 reference

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5 March 2020

issue

13

1 reference

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5 March 2020

page(s)

3830-3846

1 reference

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Mutations of optineurin in amyotrophic lateral sclerosis

5 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Adult-onset primary open-angle glaucoma caused by mutations in optineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Novel antibodies reveal inclusions containing non-native SOD1 in sporadic ALS patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Differential involvement of optineurin in amyotrophic lateral sclerosis with or without SOD1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Optineurin immunoreactivity in neuronal nuclear inclusions of polyglutamine diseases (Huntington's, DRPLA, SCA2, SCA3) and intranuclear inclusion body disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Autophagy dysregulation in amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Mutant SOD1 inhibits ER-Golgi transport in amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Extracellular wildtype and mutant SOD1 induces ER-Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

ER exit sites are physical and functional core autophagosome biogenesis components

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

The ER-Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Reduced endoplasmic reticulum (ER)-to-Golgi protein trafficking contributes to ER stress in lipotoxic mouse beta cells by promoting protein overload.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Myosin VI is an actin-based motor that moves backwards

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Myosin VI: cellular functions and motor properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Myosin VI and its cargo adaptors - linking endocytosis and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Cargo binding induces dimerization of myosin VI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Kinetic properties and small-molecule inhibition of human myosin-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Rab8-optineurin-myosin VI: analysis of interactions and functions in the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Kinetic analysis of secretory protein traffic and characterization of golgi to plasma membrane transport intermediates in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Guidelines for the use and interpretation of assays for monitoring autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

In search of an "autophagomometer".

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Cog3p depletion blocks vesicle-mediated Golgi retrograde trafficking in HeLa cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Signal integration in the endoplasmic reticulum unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Impairment of protein trafficking upon overexpression and mutation of optineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Effects of mutations and deletions in the human optineurin gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Autophagy in the Pathogenesis of Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

The role of autophagy in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Defective relocalization of ALS2/alsin missense mutants to Rac1-induced macropinosomes accounts for loss of their cellular function and leads to disturbed amphisome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

MTOR-independent, autophagic enhancer trehalose prolongs motor neuron survival and ameliorates the autophagic flux defect in a mouse model of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Clinicopathologic features of autosomal recessive amyotrophic lateral sclerosis associated with optineurin mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Myosin VI small insert isoform maintains exocytosis by tethering secretory granules to the cortical actin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Exome sequencing reveals VCP mutations as a cause of familial ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Prions disturb post-Golgi trafficking of membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Studies of optineurin, a glaucoma gene: Golgi fragmentation and cell death from overexpression of wild-type and mutant optineurin in two ocular cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Filamin-A and Myosin VI colocalize with fibrillary Tau protein in Alzheimer's disease and FTDP-17 brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Visualization of retroviral replication in living cells reveals budding into multivesicular bodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

Astrocytic TDP-43 pathology in Alexander disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV126

21 January 2018

Identifiers

DOI

10.1093/HMG/DDV126

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25859013%20AND%20SRC:MED&resulttype=core&format=json

release_5pd2rfcs6fef5fnowv2ttqvpk4

5 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5pd2rfcs6fef5fnowv2ttqvpk4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25859013%20AND%20SRC:MED&resulttype=core&format=json