(Q52699532)

6 May 2018

title

Alkaline ceramidase 2 is essential for the homeostasis of plasma sphingoid bases and their phosphates. (English)

1 reference

6 May 2018

main subject

Alkaline ceramidase 2

1 reference

GOA release 2020-03-11

12

Yusuf A Hannun

1 reference

6 May 2018

author name string

Fang Li

1

1 reference

6 May 2018

Ruijuan Xu

2

1 reference

6 May 2018

Benjamin E Low

3

1 reference

6 May 2018

Chih-Li Lin

4

1 reference

6 May 2018

Monica Garcia-Barros

5

1 reference

6 May 2018

Jennifer Schrandt

6

1 reference

6 May 2018

Izolda Mileva

7

1 reference

6 May 2018

Ashley Snider

8

1 reference

6 May 2018

Catherine K Luo

9

1 reference

6 May 2018

Xian-Cheng Jiang

10

1 reference

6 May 2018

Ming-Song Li

11

1 reference

6 May 2018

Lina M Obeid

13

1 reference

6 May 2018

Michael V Wiles

14

1 reference

6 May 2018

Cungui Mao

15

1 reference

6 May 2018

language of work or name

English

0 references

publication date

22 January 2018

1 reference

6 May 2018

published in

FASEB Journal

1 reference

6 May 2018

page(s)

fj201700445RR

1 reference

6 May 2018

Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells.

cites work

1 reference

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Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor

25 August 2018

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Sphingosine 1-Phosphate Receptor 1 Signaling in Mammalian Cells

25 August 2018

1 reference

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Acid Ceramidase Deficiency is characterized by a unique plasma cytokine and ceramide profile that is altered by therapy.

25 August 2018

1 reference

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Ceramidases, roles in sphingolipid metabolism and in health and disease

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Platelet and Erythrocyte Sources of S1P Are Redundant for Vascular Development and Homeostasis, but Both Rendered Essential After Plasma S1P Depletion in Anaphylactic Shock.

25 August 2018

1 reference

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Simple, Efficient CRISPR-Cas9-Mediated Gene Editing in Mice: Strategies and Methods

25 August 2018

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Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Erythrocyte-derived sphingosine 1-phosphate is essential for vascular development

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Sphingosine 1-phosphate signalling

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

PhotoImmunoNanoTherapy reveals an anticancer role for sphingosine kinase 2 and dihydrosphingosine-1-phosphate

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Multiplex genome engineering using CRISPR/Cas systems

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Role of palmitate-induced sphingoid base-1-phosphate biosynthesis in INS-1 β-cell survival.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Platelets in thrombosis and hemostasis: old topic with new mechanisms

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Distinct generation, pharmacology, and distribution of sphingosine 1-phosphate and dihydrosphingosine 1-phosphate in human neural progenitor cells

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Extracellular and intracellular actions of sphingosine-1-phosphate

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

UPLC-MS/MS method for analysis of sphingosine 1-phosphate in biological samples

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Opposite effects of dihydrosphingosine 1-phosphate and sphingosine 1-phosphate on transforming growth factor-beta/Smad signaling are mediated through the PTEN/PPM1A-dependent pathway

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Vascular endothelium as a contributor of plasma sphingosine 1-phosphate

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Erythrocytes store and release sphingosine 1-phosphate in blood.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Essential role for sphingosine kinases in neural and vascular development

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Egress: a receptor-regulated step in lymphocyte trafficking

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Optimal protocol for total body irradiation for allogeneic bone marrow transplantation in mice.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Processing of gene expression data generated by quantitative real-time RT-PCR.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT).

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Molecular cloning and functional characterization of murine sphingosine kinase

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

Reference intervals for serum sphingosine-1-phosphate in the population-based Study of Health in Pomerania

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5956249

30 November 2018

Identifiers

DOI

10.1096/FJ.201700445RR

1 reference

6 May 2018

0 references

1 reference

6 May 2018