(Q53025494)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Dekuang Zhao

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Manuel Picon-Ruiz

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

author name string

C Pan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

J Sun

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

C Gilbert

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

K Drews-Elger

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

M Kim

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

W Ullmer

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

D El-Ashry

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

C J Creighton

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

J M Slingerland

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

language of work or name

English

0 references

publication date

25 August 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

volume

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

issue

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

page(s)

3107-3119

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2014.257

13 March 2020

exact match

0 references

cites work

Cancer stem cells: models and concepts

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Prospective identification of tumorigenic breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Normal stem cells and cancer stem cells: the niche matters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Interactions between cancer stem cells and their niche govern metastatic colonization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Targeting the tumour vasculature: insights from physiological angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

VEGF receptor signalling - in control of vascular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Vascular endothelial growth factor modulates the transendothelial migration of MDA-MB-231 breast cancer cells through regulation of brain microvascular endothelial cell permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Pluripotent stem cell differentiation into vascular cells: a novel technology with promises for vascular re(generation).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

VEGF induces differentiation of functional endothelium from human embryonic stem cells: implications for tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Vascular endothelial growth factor receptor 3 directly regulates murine neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Angiogenic capacity of human adipose-derived stromal cells during adipogenic differentiation: an in vitro study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Eyes wide open: a critical review of sphere-formation as an assay for stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Primary breast tumor-derived cellular models: characterization of tumorigenic, metastatic, and cancer-associated fibroblasts in dissociated tumor (DT) cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Reversal of the estrogen receptor negative phenotype in breast cancer and restoration of antiestrogen response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Gene expression profile of A549 cells from tissue of 4D model predicts poor prognosis in lung cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Mammary stem cells, self-renewal pathways, and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Kruppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Downregulation of transcription factor SOX2 in cancer stem cells suppresses growth and metastasis of lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Inflammation and cancer: IL-6 and STAT3 complete the link.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Stat3 and c-Myc genome-wide promoter occupancy in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Reflecting on 25 years with MYC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Tumor-specific VEGF-A and VEGFR2 in postmenopausal breast cancer patients with long-term follow-up. Implication of a link between VEGF pathway and tamoxifen response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Angiogenesis modulates adipogenesis and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

VEGF/SDF-1 promotes cardiac stem cell mobilization and myocardial repair in the infarcted heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

A novel role for vascular endothelial growth factor as an autocrine survival factor for embryonic stem cells during hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Effect of VEGF on the regenerative capacity of muscle stem cells in dystrophic skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

VEGF targets the tumour cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Glioma tumor stem-like cells promote tumor angiogenesis and vasculogenesis via vascular endothelial growth factor and stromal-derived factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Making a tumour's bed: glioblastoma stem cells and the vascular niche.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

A perivascular niche for brain tumor stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Vascular endothelial growth factor-dependent and -independent regulation of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Regulation of Sox2 by STAT3 initiates commitment to the neural precursor cell fate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Anticancer strategies involving the vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

It takes two to tango: combinations of conventional cytotoxics with compounds targeting the vascular endothelial growth factor-vascular endothelial growth factor receptor pathway in patients with solid malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

An overview of small-molecule inhibitors of VEGFR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Bevacizumab in the treatment of metastatic breast cancer: friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Fighting fire with fire: rekindling the bevacizumab debate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Angiogenesis-independent tumor growth mediated by stem-like cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

VEGF-targeted therapy: mechanisms of anti-tumour activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Genes that mediate breast cancer metastasis to lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

A meta-analysis of human embryonic stem cells transcriptome integrated into a web-based expression atlas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Human small cell lung cancer cells express functional VEGF receptors, VEGFR-2 and VEGFR-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Sox2 expression in breast tumours and activation in breast cancer stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Vascular endothelial growth factor (VEGF) and its receptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

E2100: a phase III trial of paclitaxel versus paclitaxel/bevacizumab for metastatic breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

The changing faces of cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Vascular endothelial growth factor expression in stage I non-small cell lung cancer correlates with neoangiogenesis and a poor prognosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.257

Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25151964

12 December 2020

inferred from PubMed ID database lookup

SOX2 expression and amplification in gliomas and glioma cell lines

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25151964

12 December 2020

inferred from PubMed ID database lookup

Vascular endothelial growth factor receptor-2 in breast cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25151964

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/ONC.2014.257

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json

release_2ribt6m7wbfm5ezspbgx3hnbqi

13 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2ribt6m7wbfm5ezspbgx3hnbqi

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151964%20AND%20SRC:MED&resulttype=core&format=json