(Q53060298)

English

Opposing effects of HIF1α and HIF2α on chromaffin cell phenotypic features and tumor cell proliferation: Insights from MYC-associated factor X.

scientific article published on 7 April 2014

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scholarly article

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Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/24676840

Opposing effects of HIF1α and HIF2α on chromaffin cell phenotypic features and tumor cell proliferation: Insights from MYC-associated factor X. (English)

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Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/24676840

Massimo Mannelli

9

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PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/24676840

Giuseppe Opocher

10

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Europe PubMed Central

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11 May 2018

http://europepmc.org/abstract/MED/24676840

Mercedes Robledo

15

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11 May 2018

http://europepmc.org/abstract/MED/24676840

14

object named as

Karel Pacak

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11 May 2018

Graeme Eisenhofer

16

object named as

Graeme Eisenhofer

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11 May 2018

http://europepmc.org/abstract/MED/24676840

Jacques W M Lenders

7

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Jacques W M Lenders

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11 May 2018

http://europepmc.org/abstract/MED/24676840

Triantafyllos Chavakis

13

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Triantafyllos Chavakis

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11 May 2018

http://europepmc.org/abstract/MED/24676840

author name string

Nan Qin

1

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11 May 2018

http://europepmc.org/abstract/MED/24676840

Aguirre A de Cubas

2

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11 May 2018

http://europepmc.org/abstract/MED/24676840

Ruben Garcia-Martin

3

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11 May 2018

http://europepmc.org/abstract/MED/24676840

Susan Richter

4

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11 May 2018

http://europepmc.org/abstract/MED/24676840

Mirko Peitzsch

5

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11 May 2018

http://europepmc.org/abstract/MED/24676840

Mario Menschikowski

6

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11 May 2018

http://europepmc.org/abstract/MED/24676840

Henri J L M Timmers

8

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11 May 2018

http://europepmc.org/abstract/MED/24676840

Matina Economopoulou

11

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11 May 2018

http://europepmc.org/abstract/MED/24676840

Gabriele Siegert

12

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11 May 2018

http://europepmc.org/abstract/MED/24676840

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publication date

7 April 2014

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11 May 2018

http://europepmc.org/abstract/MED/24676840

International Journal of Cancer

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11 May 2018

http://europepmc.org/abstract/MED/24676840

135

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11 May 2018

http://europepmc.org/abstract/MED/24676840

9

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11 May 2018

http://europepmc.org/abstract/MED/24676840

2054-2064

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11 May 2018

http://europepmc.org/abstract/MED/24676840

The mycn/max protein complex in neuroblastoma. Short review

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Myc-Max-Mad: a transcription factor network controlling cell cycle progression, differentiation and death

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Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma

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Hypoxia-inducible factor signaling in pheochromocytoma: turning the rudder in the right direction

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A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

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Distinct gene expression profiles in norepinephrine- and epinephrine-producing hereditary and sporadic pheochromocytomas: activation of hypoxia-driven angiogenic pathways in von Hippel-Lindau syndrome

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Research resource: Transcriptional profiling reveals different pseudohypoxic signatures in SDHB and VHL-related pheochromocytomas

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Why is the adrenal adrenergic?

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HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity

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HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma

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Metabolic reprogramming and two-compartment tumor metabolism: opposing role(s) of HIF1α and HIF2α in tumor-associated fibroblasts and human breast cancer cells

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Endothelial cell HIF-1α and HIF-2α differentially regulate metastatic success

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Opposing roles for HIF-1α and HIF-2α in the regulation of angiogenesis by mononuclear phagocytes

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The opposing effect of hypoxia-inducible factor-2alpha on expression of telomerase reverse transcriptase.

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HIF-1alpha and HIF-2alpha have divergent roles in colon cancer.

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Pheochromocytoma cell lines from heterozygous neurofibromatosis knockout mice.

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High-efficiency transfection of mammalian neurons via nucleofection

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21 January 2018

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

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21 January 2018

Double stable isotope ultra performance liquid chromatographic-tandem mass spectrometric quantification of tissue content and activity of phenylethanolamine N-methyltransferase, the crucial enzyme responsible for synthesis of epinephrine

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21 January 2018

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations

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21 January 2018

Expression of HIF-1alpha, HIF-2alpha (EPAS1), and their target genes in paraganglioma and pheochromocytoma with VHL and SDH mutations.

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21 January 2018

The Warburg effect is genetically determined in inherited pheochromocytomas

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21 January 2018

Comparative studies of PC12 and mouse pheochromocytoma-derived rodent cell lines as models for the study of neuroendocrine systems.

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21 January 2018

Adrenergic differentiation potential in PC12 cells: influence of sodium butyrate and dexamethasone.

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21 January 2018

Hypoxia activates multiple transcriptional pathways in mouse pheochromocytoma cells

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21 January 2018

The neurotrophic activity of fibroblast growth factor 1 (FGF1) depends on endogenous FGF1 expression and is independent of the mitogen-activated protein kinase cascade pathway

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21 January 2018

The HINT1 tumor suppressor regulates both gamma-H2AX and ATM in response to DNA damage

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21 January 2018

DUSP6 is a novel transcriptional target of p53 and regulates p53-mediated apoptosis by modulating expression levels of Bcl-2 family proteins

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21 January 2018

Catecholamine biosynthesis and secretion: physiological and pharmacological effects of secretin.

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21 January 2018

Regulation of neurotensin content in adrenal medullary cells: comparison of PC12 cells to normal rat chromaffin cells in vitro

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21 January 2018

Neurotensin induces tyrosine hydroxylase gene activation through nitric oxide and protein kinase C signaling pathways.

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21 January 2018

Role of hypoxia and HIF2α in development of the sympathoadrenal cell lineage and chromaffin cell tumors with distinct catecholamine phenotypic features

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21 January 2018

The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development

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21 January 2018

Cloning and expression pattern of EPAS1 in the chicken embryo. Colocalization with tyrosine hydroxylase

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21 January 2018

HIF-2alpha expression in human fetal paraganglia and neuroblastoma: relation to sympathetic differentiation, glucose deficiency, and hypoxia.

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21 January 2018

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

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21 January 2018

Somatic HIF2A gain-of-function mutations in paraganglioma with polycythemia

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Mosaicism in HIF2A-related polycythemia-paraganglioma syndrome.

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Hypoxic stress-induced changes in adrenergic function: role of HIF1 alpha

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Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

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21 January 2018

SDH mutations establish a hypermethylator phenotype in paraganglioma.

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Plasma methoxytyramine: a novel biomarker of metastatic pheochromocytoma and paraganglioma in relation to established risk factors of tumour size, location and SDHB mutation status

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MAX Mutations Cause Hereditary and Sporadic Pheochromocytoma and Paraganglioma

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Integrative genomic analysis reveals somatic mutations in pheochromocytoma and paraganglioma

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c-Myc Does Not Require Max for Transcriptional Activity in PC-12 Cells

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Identifiers

10.1002/IJC.28868

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/24676840

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/24676840

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