(Q53077895)

11 May 2018

title

Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization from Acidic Stores in Pancreatic α-Cells. (English)

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11 May 2018

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16

Patrik Rorsman

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11 May 2018

Jakob G Knudsen

5

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Andrei I Tarasov

Andrei I Tarasov

17

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Guy A. Rutter

Guy A Rutter

14

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Manuela Zaccolo

Manuela Zaccolo

10

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Antony Giuseppe Galione

Antony Galione

15

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Albert Salehi

3

Albert Salehi

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11 May 2018

Paul Johnson

12

Paul R V Johnson

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11 May 2018

Reshma D Ramracheya

13

Reshma Ramracheya

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11 May 2018

author name string

Alexander Hamilton

1

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11 May 2018

Quan Zhang

2

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11 May 2018

Mara Willems

4

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11 May 2018

Anna K Ringgaard

6

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11 May 2018

Caroline E Chapman

7

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11 May 2018

Alejandro Gonzalez-Alvarez

8

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11 May 2018

Nicoletta C Surdo

9

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11 May 2018

Davide Basco

11

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11 May 2018

language of work or name

English

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publication date

21 March 2018

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11 May 2018

published in

Diabetes

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11 May 2018

Adrenergic modulation of pancreatic A, B, and D cells alpha-Adrenergic suppression and beta-adrenergic stimulation of somatostatin secretion, alpha-adrenergic stimulation of glucagon secretion in the perfused dog pancreas

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Adrenaline stimulates glucagon secretion in pancreatic A-cells by increasing the Ca2+ current and the number of granules close to the L-type Ca2+ channels

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Xestospongins: potent membrane permeable blockers of the inositol 1,4,5-trisphosphate receptor

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Coordination of agonist-induced Ca2+-signalling patterns by NAADP in pancreatic acinar cells

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cAMP-GEFII is a direct target of cAMP in regulated exocytosis

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Hypoglycaemia: the limiting factor in the glycaemic management of Type I and Type II diabetes

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The beta-adrenergic receptors

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12 December 2020

Involvement of alpha1 and beta-adrenoceptors in adrenaline stimulation of the glucagon-secreting mouse alpha-cell

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A store-operated mechanism determines the activity of the electrically excitable glucagon-secreting pancreatic alpha-cell

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Long-term mortality in a nationwide cohort of childhood-onset type 1 diabetic patients in Norway

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Subcellular dynamics of protein kinase A activity visualized by FRET-based reporters

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Glucose inhibits glucagon secretion by a direct effect on mouse pancreatic alpha cells

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Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains

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Hypoglycemia, functional brain failure, and brain death

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Monitoring calcium concentration in neurons with cameleon

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Glutamate is a positive autocrine signal for glucagon release

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12 December 2020

Identification of a chemical probe for NAADP by virtual screening

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12 December 2020

NAADP mobilizes calcium from acidic organelles through two-pore channels

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12 December 2020

GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis

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12 December 2020

A role for islet somatostatin in mediating sympathetic regulation of glucagon secretion

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Innervation patterns of autonomic axons in the human endocrine pancreas

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12 December 2020

Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?

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Minireview: The role of the autonomic nervous system in mediating the glucagon response to hypoglycemia

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TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes

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12 December 2020

Ultrasensitive fluorescent proteins for imaging neuronal activity

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12 December 2020

Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes

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12 December 2020

ATP-regulated potassium channels and voltage-gated calcium channels in pancreatic alpha and beta cells: similar functions but reciprocal effects on secretion

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12 December 2020

A primer of NAADP-mediated Ca(2+) signalling: From sea urchin eggs to mammalian cells

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12 December 2020

Expression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells

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12 December 2020

Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets

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12 December 2020

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells.

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12 December 2020

Two-pore Channels (TPC2s) and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) at Lysosomal-Sarcoplasmic Reticular Junctions Contribute to Acute and Chronic β-Adrenoceptor Signaling in the Heart

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12 December 2020

Exciting Times for Pancreatic Islets: Glutamate Signaling in Endocrine Cells

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12 December 2020

The two pore channel TPC2 is dispensable in pancreatic β-cells for normal Ca²⁺ dynamics and insulin secretion

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12 December 2020

Characterization of Two-Pore Channel 2 by Nuclear Membrane Electrophysiology

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12 December 2020

Early sympathetic islet neuropathy in autoimmune diabetes: lessons learned and opportunities for investigation.

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12 December 2020

Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

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12 December 2020

Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets.

1 reference

12 December 2020

Synthesis of the Ca2+-mobilizing messengers NAADP and cADPR by intracellular CD38 enzyme in the mouse heart: Role in β-adrenoceptor signaling

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB17-1102

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11 May 2018

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1 reference

11 May 2018