(Q53080575)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

SHP2 inhibition restores sensitivity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Luc Friboulet

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Melissa Parks

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

13

Adam Langenbucher

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

author name string

Leila Dardaei

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Hui Qin Wang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Manrose Singh

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Paul Fordjour

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Katherine X Shaw

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Grainne Kerr

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Kristine Yu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Jinsheng Liang

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Yichen Cao

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Yan Chen

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Michael S Lawrence

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Justin F Gainor

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Ibiayi Dagogo-Jack

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

David T Myers

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Emma Labrot

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

David Ruddy

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Dana Lee

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Richard H DiCecca

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Susan Moody

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Huaixiang Hao

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Morvarid Mohseni

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Matthew LaMarche

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Juliet Williams

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Keith Hoffmaster

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Giordano Caponigro

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Alice T Shaw

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Aaron N Hata

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Cyril H Benes

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Fang Li

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Jeffrey A Engelman

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

language of work or name

English

0 references

publication date

5 March 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

volume

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

page(s)

512-517

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nm.4497

19 March 2020

exact match

0 references

cites work

First-line crizotinib versus chemotherapy in ALK-positive lung cancer

1 reference

7 January 2021

Crizotinib versus chemotherapy in advanced ALK-positive lung cancer.

1 reference

7 January 2021

Ceritinib in ALK-rearranged non-small-cell lung cancer

1 reference

7 January 2021

Treating ALK-positive lung cancer--early successes and future challenges

1 reference

7 January 2021

Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer

1 reference

7 January 2021

PF-06463922, an ALK/ROS1 Inhibitor, Overcomes Resistance to First and Second Generation ALK Inhibitors in Preclinical Models

1 reference

7 January 2021

EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors.

1 reference

7 January 2021

Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer.

1 reference

7 January 2021

Therapeutic strategies to overcome crizotinib resistance in non-small cell lung cancers harboring the fusion oncogene EML4-ALK.

1 reference

7 January 2021

Mechanisms of acquired crizotinib resistance in ALK-rearranged lung Cancers

1 reference

7 January 2021

Heterogeneity of genetic changes associated with acquired crizotinib resistance in ALK-rearranged lung cancer.

1 reference

7 January 2021

A novel ALK secondary mutation and EGFR signaling cause resistance to ALK kinase inhibitors

1 reference

7 January 2021

Patient-derived models of acquired resistance can identify effective drug combinations for cancer.

1 reference

7 January 2021

Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer

1 reference

7 January 2021

Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression

1 reference

7 January 2021

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

1 reference

7 January 2021

Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity

1 reference

7 January 2021

Shp2 regulates SRC family kinase activity and Ras/Erk activation by controlling Csk recruitment

1 reference

7 January 2021

The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

1 reference

7 January 2021

Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras

1 reference

7 January 2021

SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases

1 reference

7 January 2021

Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation

1 reference

7 January 2021

Genetic analysis of protein tyrosine phosphatases

1 reference

7 January 2021

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor

1 reference

7 January 2021

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

1 reference

7 January 2021

Regulation of the mitogen-activated protein kinase signaling pathway by SHP2.

1 reference

7 January 2021

(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway

1 reference

7 January 2021

Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer

1 reference

7 January 2021

RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM.4497

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29505033%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference