(Q53129033)

11 May 2018

title

Rapid oligomer formation of human muscle acylphosphatase induced by heparan sulfate. (English)

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11 May 2018

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Francesco Bemporad

8

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Alessandra Corazza

Alessandra Corazza

6

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Federico Fogolari

Federico Fogolari

5

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Annalisa Relini

4

Annalisa Relini

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11 May 2018

Amanda Penco

3

Amanda Penco

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11 May 2018

author name string

Neda Motamedi-Shad

1

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11 May 2018

Tommaso Garfagnini

2

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11 May 2018

Gennaro Esposito

7

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11 May 2018

Fabrizio Chiti

9

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11 May 2018

publication date

22 April 2012

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11 May 2018

Nature Structural & Molecular Biology

published in

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11 May 2018

volume

19

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11 May 2018

issue

5

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11 May 2018

page(s)

547-54, S1-2

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11 May 2018

Protein misfolding, functional amyloid, and human disease

cites work

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Amyloid accomplices and enforcers

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Amyloidogenesis: historical and modern observations point to heparan sulfate proteoglycans as a major culprit

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Glycosaminoglycans in extracts of cardiac amyloid fibrils from familial amyloid cardiomyopathy of Danish origin related to variant transthyretin Met 111.

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The ultrastructural localization of sulfated proteoglycans is identical in the amyloids of Alzheimer's disease and AA, AL, senile cardiac and medullary carcinoma-associated amyloidosis

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An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistence of fibrillar A beta-amyloid in rat brain

21 January 2018

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Sulfate content and specific glycosaminoglycan backbone of perlecan are critical for perlecan's enhancement of islet amyloid polypeptide (amylin) fibril formation

21 January 2018

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Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from alpha-synuclein in vitro.

21 January 2018

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Agrin binds to beta-amyloid (Abeta), accelerates abeta fibril formation, and is localized to Abeta deposits in Alzheimer's disease brain

21 January 2018

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Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans

21 January 2018

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Circular-dichroism studies on two murine serum amyloid A proteins

21 January 2018

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Interactions of Alzheimer amyloid-beta peptides with glycosaminoglycans effects on fibril nucleation and growth

21 January 2018

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Heparin accelerates gelsolin amyloidogenesis

21 January 2018

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Proteoglycan-mediated inhibition of A beta proteolysis. A potential cause of senile plaque accumulation.

21 January 2018

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Glycosaminoglycan and proteoglycan inhibit the depolymerization of beta2-microglobulin amyloid fibrils in vitro

21 January 2018

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Sulfated glycans and elevated temperature stimulate PrP(Sc)-dependent cell-free formation of protease-resistant prion protein

21 January 2018

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The sulfate moieties of glycosaminoglycans are critical for the enhancement of beta-amyloid protein fibril formation

21 January 2018

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Effects of sulfate ions on Alzheimer beta/A4 peptide assemblies: implications for amyloid fibril-proteoglycan interactions

21 January 2018

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Agrin binds alpha-synuclein and modulates alpha-synuclein fibrillation.

21 January 2018

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Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein

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Role of glycosaminoglycan sulfation in the formation of immunoglobulin light chain amyloid oligomers and fibrils

21 January 2018

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Heparin binds 8 kDa gelsolin cross-β-sheet oligomers and accelerates amyloidogenesis by hastening fibril extension

21 January 2018

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A causative link between the structure of aberrant protein oligomers and their toxicity.

21 January 2018

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21 January 2018

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21 January 2018

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

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21 January 2018

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21 January 2018

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Kinetic analysis of amyloid formation in the presence of heparan sulfate: faster unfolding and change of pathway

21 January 2018

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Amyloid formation by pro-islet amyloid polypeptide processing intermediates: examination of the role of protein heparan sulfate interactions and implications for islet amyloid formation in type 2 diabetes

21 January 2018

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Heparin-protein interactions

21 January 2018

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A computational approach for identifying the chemical factors involved in the glycosaminoglycans-mediated acceleration of amyloid fibril formation

21 January 2018

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Arginine-23 is involved in the catalytic site of muscle acylphosphatase.

21 January 2018

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Expression, purification, and characterization of acylphosphatase muscular isoenzyme as fusion protein with glutathione S-transferase.

21 January 2018

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Slow folding of muscle acylphosphatase in the absence of intermediates.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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N.m.r. and molecular-modelling studies of the solution conformation of heparin

21 January 2018

1 reference

Perlecan binds to the beta-amyloid proteins (A beta) of Alzheimer's disease, accelerates A beta fibril formation, and maintains A beta fibril stability.

21 January 2018

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Characterization of tissue and plasma glycosaminoglycans during experimental AA amyloidosis and acute inflammation. Qualitative and quantitative analysis.

31 March 2020

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12 December 2020

Structural prerequisites for serum amyloid A fibril formation

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12 December 2020

Python: a programming language for software integration and development

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12 December 2020

The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease

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12 December 2020

Cortical tissue of patients with hereditary cerebral hemorrhage with amyloidosis (Dutch) contains various extracellular matrix deposits

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12 December 2020

Immunolocalization of heparan sulfate proteoglycans to the prion protein amyloid plaques of Gerstmann-Straussler syndrome, Creutzfeldt-Jakob disease and scrapie

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12 December 2020

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

1 reference

12 December 2020

Localization of the basement membrane heparan sulfate proteoglycan in islet amyloid deposits in type II diabetes mellitus

1 reference

12 December 2020

Identifiers

DOI

10.1038/NSMB.2286

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11 May 2018

Dimensions Publication ID

1053338383

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11 May 2018