(Q53227600)

English

Concomitant activation of AKT with extracellular-regulated kinase 1/2 occurs independently of PTEN or PIK3CA mutations in endometrial cancer and may be associated with favorable prognosiss.

scientific article published on 9 October 2007

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scholarly article

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

Concomitant activation of AKT with extracellular-regulated kinase 1/2 occurs independently of PTEN or PIK3CA mutations in endometrial cancer and may be associated with favorable prognosiss. (English)

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

endometrial cancer

1 reference

based on heuristic

inferred from title

author name string

Noriko Mori

1

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

Satoru Kyo

2

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

Junko Sakaguchi

3

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

Yasunari Mizumoto

4

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

Satoshi Ohno

5

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

Yoshiko Maida

6

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

Manabu Hashimoto

7

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

Masahiro Takakura

8

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

Masaki Inoue

9

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

publication date

9 October 2007

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

98

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

12

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

1881-1888

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Association of mismatch repair deficiency with PTEN frameshift mutations in endometrial cancers and the precursors in a Japanese population.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

PI3K: downstream AKTion blocks apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Ras signalling and apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

High frequency of mutations of the PIK3CA gene in human cancers

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

PIK3CA gene mutations in endometrial carcinoma: correlation with PTEN and K-RAS alterations.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Ras, PI(3)K and mTOR signalling controls tumour cell growth

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Mammalian MAP kinase signalling cascades

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Activation of ERK1/2 occurs independently of KRAS or BRAF status in endometrial cancer and is associated with favorable prognosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Creation of tumorigenic human endometrial epithelial cells with intact chromosomes by introducing defined genetic elements

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

The role of PTEN and its signalling pathways, including AKT, in breast cancer; an assessment of relationships with other prognostic factors and with outcome.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Somatic mutation and gain of copy number of PIK3CA in human breast cancer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Mutations of PIK3CA in gastric adenocarcinoma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

PIK3CA mutations in advanced ovarian carcinomas

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Expression of EGFR, HER-2/neu, P53, and PCNA in endometrioid, serous papillary, and clear cell endometrial adenocarcinomas

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Inhibition of ligand-independent ERK1/2 activity in kidney proximal tubular cells deprived of soluble survival factors up-regulates Akt and prevents apoptosis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Regulation of Raf-Akt Cross-talk

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Prognostic significance of activated Akt expression in melanoma: a clinicopathologic study of 292 cases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Phosphorylation of Akt (Ser473) is an excellent predictor of poor clinical outcome in prostate cancer.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2007.00630.X

21 January 2018

Identifiers

10.1111/J.1349-7006.2007.00630.X

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/17924977

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