(Q53259451)

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Cleavage of the vesicular GABA transporter under excitotoxic conditions is followed by accumulation of the truncated transporter in nonsynaptic sites.

scientific article published in March 2011

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26 January 2020

Cleavage of the vesicular GABA transporter under excitotoxic conditions is followed by accumulation of the truncated transporter in nonsynaptic sites (English)

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26 January 2020

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Carlos B. Duarte

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26 January 2020

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26 January 2020

Tadeusz Wieloch

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26 January 2020

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Ana R Inácio

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26 January 2020

Jiro Takano

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26 January 2020

Nobuhisa Iwata

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26 January 2020

Takaomi C Saido

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26 January 2020

Andrea C Lobo

2

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26 January 2020

Carlos V Melo

3

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26 January 2020

Luís P de Almeida

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26 January 2020

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1 March 2011

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26 January 2020

Journal of Neuroscience

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26 January 2020

31

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26 January 2020

12

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26 January 2020

4622-4635

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26 January 2020

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6622902/fullTextXML

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Presence of the vesicular inhibitory amino acid transporter in GABAergic and glycinergic synaptic terminal boutons

1 reference

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12 December 2020

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Caspase and calpain substrates: roles in synaptic plasticity and cell death

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The PEST domain of IkappaBalpha is necessary and sufficient for in vitro degradation by mu-calpain

1 reference

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12 December 2020

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Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates

1 reference

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12 December 2020

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Immunoisolation of GABA-specific synaptic vesicles defines a functionally distinct subset of synaptic vesicles.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21430162

12 December 2020

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Constitutive phosphorylation of the vesicular inhibitory amino acid transporter in rat central nervous system

1 reference

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gamma-Aminobutyric acid(A) neurotransmission and cerebral ischemia

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A new mathematical model for relative quantification in real-time RT-PCR

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Expression of the vesicular inhibitory amino acid transporter in pancreatic islet cells: distribution of the transporter within rat islets

1 reference

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12 December 2020

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Proteasomal inhibition-induced inclusion formation and death in cortical neurons require transcription and ubiquitination

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Gene expression analysis of spontaneously hypertensive rat cerebral cortex following transient focal cerebral ischemia

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In vivo role of caspases in excitotoxic neuronal death: generation and analysis of transgenic mice expressing baculoviral caspase inhibitor, p35, in postnatal neurons

1 reference

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12 December 2020

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Mouse vesicular GABA transporter gene: genomic organization, transcriptional regulation and chromosomal localization

1 reference

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12 December 2020

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Animal models of focal and global cerebral ischemia

1 reference

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12 December 2020

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The calpain system

1 reference

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12 December 2020

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On the sequential determinants of calpain cleavage

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12 December 2020

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Some precautions in using chelators to buffer metals in biological solutions

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https://pubmed.ncbi.nlm.nih.gov/21430162

12 December 2020

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Sequential release of GABA by exocytosis and reversed uptake leads to neuronal swelling in simulated ischemia of hippocampal slices.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21430162

12 December 2020

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Blue silver: a very sensitive colloidal Coomassie G-250 staining for proteome analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21430162

12 December 2020

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High Ca(2+)-phosphate transfection efficiency enables single neuron gene analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21430162

12 December 2020

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Calpain mediates excitotoxic DNA fragmentation via mitochondrial pathways in adult brains: evidence from calpastatin mutant mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21430162

12 December 2020

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Distinct mechanistic roles of calpain and caspase activation in neurodegeneration as revealed in mice overexpressing their specific inhibitors.

1 reference

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12 December 2020

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Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats

1 reference

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12 December 2020

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Prolonged positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors induces calpain-mediated PSD-95/Dlg/ZO-1 protein degradation and AMPA receptor down-regulation in cultured hippocampal slices

1 reference

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12 December 2020

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The mouse vesicular inhibitory amino acid transporter gene: expression during embryogenesis, analysis of its core promoter in neural stem cells and a reconsideration of its alternate splicing

1 reference

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12 December 2020

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Neuroprotection by BDNF against glutamate-induced apoptotic cell death is mediated by ERK and PI3-kinase pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21430162

12 December 2020

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Enriched environment enhances recovery of motor function after focal ischemia in mice, and downregulates the transcription factor NGFI-A.

1 reference

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12 December 2020

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Decreased expression of vesicular GABA transporter, but not vesicular glutamate, acetylcholine and monoamine transporters in rat brain following focal ischemia

1 reference

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12 December 2020

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Kainic acid-mediated excitotoxicity as a model for neurodegeneration

1 reference

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12 December 2020

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Presynaptic regulation of quantal size by the vesicular glutamate transporter VGLUT1.

1 reference

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Proteasome inhibition elicits a biphasic effect on neuronal apoptosis via differential regulation of pro-survival and pro-apoptotic transcription factors

1 reference

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12 December 2020

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Identification and characterization of a novel isoform of the vesicular gamma-aminobutyric acid transporter with glucose-regulated expression in rat islets

1 reference

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12 December 2020

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Calpain-cleaved collapsin response mediator protein-3 induces neuronal death after glutamate toxicity and cerebral ischemia.

1 reference

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Activity-dependent regulation of vesicular glutamate and GABA transporters: a means to scale quantal size

1 reference

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12 December 2020

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Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors

1 reference

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12 December 2020

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Calpain-mediated mGluR1alpha truncation: a key step in excitotoxicity

1 reference

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Brain-derived neurotrophic factor regulates the expression and synaptic delivery of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits in hippocampal neurons

1 reference

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12 December 2020

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The origin of quantal size variation: vesicular glutamate concentration plays a significant role.

1 reference

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12 December 2020

based on heuristic

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Culturing hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/21430162

12 December 2020

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The phosphorylation state of GluR1 subunits determines the susceptibility of AMPA receptors to calpain cleavage

1 reference

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12 December 2020

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Excitotoxicity and focal cerebral ischemia induce truncation of the NR2A and NR2B subunits of the NMDA receptor and cleavage of the scaffolding protein PSD-95.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21430162

12 December 2020

based on heuristic

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Comparison between measured and calculated ionised concentrations in Mg2+ /ATP, Mg2+ /EDTA and Ca2+ /EGTA buffers; influence of changes in temperature, pH and pipetting errors on the ionised concentrations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21430162

12 December 2020

based on heuristic

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UNC-46 is required for trafficking of the vesicular GABA transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/21430162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21430162

12 December 2020

based on heuristic

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The neurotransmitter cycle and quantal size

1 reference

https://pubmed.ncbi.nlm.nih.gov/21430162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanistic role of calpains in postischemic neurodegeneration

1 reference

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12 December 2020

based on heuristic

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Calpain activation is involved in early caspase-independent neurodegeneration in the hippocampus following status epilepticus

1 reference

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12 December 2020

based on heuristic

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Prediction of disordered regions in proteins based on the meta approach

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Trafficking of vesicular neurotransmitter transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/21430162

12 December 2020

based on heuristic

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Validation of internal control genes for expression studies: effects of the neurotrophin BDNF on hippocampal neurons

1 reference

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Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration

1 reference

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Unique luminal localization of VGAT-C terminus allows for selective labeling of active cortical GABAergic synapses

1 reference

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Hippocampal distribution of vesicular glutamate transporter 1 in patients with temporal lobe epilepsy.

1 reference

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12 December 2020

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Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP

1 reference

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based on heuristic

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Calcium, ischemia and excitotoxicity.

1 reference

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Quantal release of acetylcholine in mice with reduced levels of the vesicular acetylcholine transporter

1 reference

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Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1 reference

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based on heuristic

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Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

1 reference

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12 December 2020

based on heuristic

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PEST motifs are not required for rapid calpain-mediated proteolysis of c-fos protein

1 reference

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12 December 2020

based on heuristic

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PEST sequences and regulation by proteolysis

1 reference

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12 December 2020

based on heuristic

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Probing the partly folded states of proteins by limited proteolysis

1 reference

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Inhibition of ischemia-induced fodrin breakdown by a novel phenylpyrimidine derivative NS-7: an implication for its neuroprotective action in rats with middle cerebral artery occlusion.

1 reference

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based on heuristic

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Identification and characterization of the vesicular GABA transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/21430162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3541-10.2011

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21430162%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21430162%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21430162%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

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