(Q53275436)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21233840%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

PP2A impaired activity is a common event in acute myeloid leukemia and its activation by forskolin has a potent anti-leukemic effect (English)

1 reference

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20 January 2020

1 reference

acute myeloid leukemia

1 reference

5

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20 January 2020

author name string

I Cristóbal

1

1 reference

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20 January 2020

L Garcia-Orti

2

1 reference

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20 January 2020

C Cirauqui

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21233840%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

M M Alonso

4

1 reference

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20 January 2020

M D Odero

6

1 reference

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20 January 2020

publication date

14 January 2011

1 reference

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20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21233840%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

25

1 reference

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20 January 2020

issue

4

1 reference

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20 January 2020

page(s)

606-614

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https://scigraph.springernature.com/pub.10.1038/leu.2010.294

20 January 2020

exact match

0 references

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Multiple pathways regulated by the tumor suppressor PP2A in transformation

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The glycine 90 to aspartate alteration in the Abeta subunit of PP2A (PPP2R1B) associates with breast cancer and causes a deficit in protein function

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Alterations in the suppressor gene PPP2R1B in parathyroid hyperplasias and adenomas

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The tumor suppressor PP2A Abeta regulates the RalA GTPase

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The role of PP2A A subunits in tumor suppression

21 January 2018

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Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation

21 January 2018

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Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis

21 January 2018

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Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A.

21 January 2018

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B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK

21 January 2018

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Identification of specific PP2A complexes involved in human cell transformation

21 January 2018

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A B56gamma mutation in lung cancer disrupts the p53-dependent tumor-suppressor function of protein phosphatase 2A

21 January 2018

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A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55

21 January 2018

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The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein

21 January 2018

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FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia

21 January 2018

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CIP2A inhibits PP2A in human malignancies

21 January 2018

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Determinants for the interaction between Janus kinase 2 and protein phosphatase 2A.

21 January 2018

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The level of AKT phosphorylation on threonine 308 but not on serine 473 is associated with high-risk cytogenetics and predicts poor overall survival in acute myeloid leukaemia.

21 January 2018

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Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancers

21 January 2018

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21 January 2018

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Induction of human promyelocytic leukemia HL-60 cell differentiation into monocytes by arsenic sulphide: involvement of serine/threonine protein phosphatases

21 January 2018

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Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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7 January 2021

Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms

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7 January 2021

Alterations of tumour suppressor gene PPP2R1B in hepatocellular carcinoma

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7 January 2021

Cancer-associated PP2A Aalpha subunits induce functional haploinsufficiency and tumorigenicity

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7 January 2021

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

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7 January 2021

Cryptic chromosome 9q34 deletion generates TAF-Ialpha/CAN and TAF-Ibeta/CAN fusion transcripts in acute myeloid leukemia

1 reference

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7 January 2021

Identifiers

DOI

10.1038/LEU.2010.294

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21233840%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference