(Q53280611)

English

Accumulative copy number increase of MET drives tumor development and histological progression in a subset of ovarian clear-cell adenocarcinomas.

scientific article published on 7 October 2011

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scholarly article

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/21983935

Accumulative copy number increase of MET drives tumor development and histological progression in a subset of ovarian clear-cell adenocarcinomas. (English)

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/21983935

1 reference

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object named as

Hitoshi Tsuda

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/21983935

4

object named as

Masashi Takano

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/21983935

Osamu Matsubara

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object named as

Osamu Matsubara

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/21983935

author name string

Sohei Yamamoto

1

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/21983935

Kosuke Miyai

3

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/21983935

Seiichi Tamai

5

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Europe PubMed Central

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http://europepmc.org/abstract/MED/21983935

publication date

7 October 2011

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/21983935

Modern Pathology

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/21983935

25

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http://europepmc.org/abstract/MED/21983935

1

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http://europepmc.org/abstract/MED/21983935

122-130

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/21983935

https://scigraph.springernature.com/pub.10.1038/modpathol.2011.143

0 references

c-Met: structure, functions and potential for therapeutic inhibition

1 reference

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Targeting the c-Met signaling pathway in cancer

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Met, metastasis, motility and more

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Novel mutations of the MET proto-oncogene in papillary renal carcinomas.

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Frequent amplification of the c-met gene in scirrhous type stomach cancer.

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Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis

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MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib

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Do clear cell ovarian carcinomas have poorer prognosis compared to other epithelial cell types? A study of 1411 clear cell ovarian cancers

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Long-term follow-up and prognostic factor analysis in clear cell adenocarcinoma of the ovary

1 reference

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Clear cell carcinoma of the ovary: a retrospective multicentre experience of 254 patients with complete surgical staging.

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Cumulative alterations of p27-related cell-cycle regulators in the development of endometriosis-associated ovarian clear cell adenocarcinoma.

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The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory

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Ovarian clear cell adenocarcinoma: a continuing enigma

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Development of automated brightfield double in situ hybridization (BDISH) application for HER2 gene and chromosome 17 centromere (CEN 17) for breast carcinomas and an assay performance comparison to manual dual color HER2 fluorescence in situ hybrid

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Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer

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Assessment of methods for tissue-based detection of the HER-2/neu alteration in human breast cancer: a direct comparison of fluorescence in situ hybridization and immunohistochemistry

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Comparison of c-met expression in ovarian epithelial tumors and normal epithelia of the female reproductive tract by quantitative laser scan microscopy

1 reference

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21 January 2018

An orally available small-molecule inhibitor of c-Met, PF-2341066, reduces tumor burden and metastasis in a preclinical model of ovarian cancer metastasis

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Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer.

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Expression and mutational analysis of MET in human solid cancers

1 reference

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21 January 2018

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2011.143

21 January 2018

Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752

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21 January 2018

NK4 (HGF-antagonist/angiogenesis inhibitor) in cancer biology and therapeutics

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AMG 102, a fully human anti-hepatocyte growth factor/scatter factor neutralizing antibody, enhances the efficacy of temozolomide or docetaxel in U-87 MG cells and xenografts

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2011.143

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Clear cell adenocarcinoma with a component of poorly differentiated histology: a poor prognostic subgroup of ovarian clear cell adenocarcinoma

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21 January 2018

Evaluation of the tyrosine kinase domain of the Met proto-oncogene in sporadic ovarian carcinomas*

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7 January 2021

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Amplification of growth factor receptor genes and DNA ploidy pattern in the progression of gastric cancer

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Genomic amplification of MET with boundaries within fragile site FRA7G and upregulation of MET pathways in esophageal adenocarcinoma

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7 January 2021

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Gene amplification and protein overexpression of MET are common events in ovarian clear-cell adenocarcinoma: their roles in tumor progression and prognostication of the patient

1 reference

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7 January 2021

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Clear cell epithelial ovarian cancer (mesonephroid): bad prognosis only in early stages

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2011.143

7 January 2021

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Molecular genetic evidence that endometriosis is a precursor of ovarian cancer

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7 January 2021

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Ovarian atypical endometriosis: its close association with malignant epithelial tumours

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2011.143

7 January 2021

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Expression of platelet-derived growth factors and their receptors in ovarian clear-cell carcinoma and its putative precursors

1 reference

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7 January 2021

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Immunopathogenesis of pelvic endometriosis: role of hepatocyte growth factor, macrophages and ovarian steroids.

1 reference

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7 January 2021

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c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion

1 reference

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7 January 2021

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Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression

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7 January 2021

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Identifiers

10.1038/MODPATHOL.2011.143

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/21983935

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/21983935

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