(Q53291157)

English

Src family kinase inhibitor PP2 efficiently inhibits cervical cancer cell proliferation through down-regulating phospho-Src-Y416 and phospho-EGFR-Y1173.

scientific article published on 4 November 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

13 May 2018

http://europepmc.org/abstract/MED/21052789

Src family kinase inhibitor PP2 efficiently inhibits cervical cancer cell proliferation through down-regulating phospho-Src-Y416 and phospho-EGFR-Y1173. (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 May 2018

http://europepmc.org/abstract/MED/21052789

cervix uterine cancer

1 reference

based on heuristic

inferred from title

author name string

Lu Kong

1

1 reference

Europe PubMed Central

PubMed publication ID

13 May 2018

http://europepmc.org/abstract/MED/21052789

Zhihong Deng

2

1 reference

Europe PubMed Central

PubMed publication ID

13 May 2018

http://europepmc.org/abstract/MED/21052789

Haiying Shen

3

1 reference

Europe PubMed Central

PubMed publication ID

13 May 2018

http://europepmc.org/abstract/MED/21052789

Yuxiang Zhang

4

1 reference

Europe PubMed Central

PubMed publication ID

13 May 2018

http://europepmc.org/abstract/MED/21052789

publication date

4 November 2010

1 reference

Europe PubMed Central

PubMed publication ID

13 May 2018

http://europepmc.org/abstract/MED/21052789

Molecular and Cellular Biochemistry

1 reference

Europe PubMed Central

PubMed publication ID

13 May 2018

http://europepmc.org/abstract/MED/21052789

348

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Europe PubMed Central

PubMed publication ID

13 May 2018

http://europepmc.org/abstract/MED/21052789

1-2

1 reference

Europe PubMed Central

PubMed publication ID

13 May 2018

http://europepmc.org/abstract/MED/21052789

11-19

1 reference

Europe PubMed Central

PubMed publication ID

13 May 2018

http://europepmc.org/abstract/MED/21052789

https://scigraph.springernature.com/pub.10.1007/s11010-010-0632-1

0 references

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src tyrosine kinase inhibitor PP2 suppresses ERK1/2 activation and epidermal growth factor receptor transactivation by X-irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both EGFR kinase and Src-related tyrosine kinases regulate human ether-à-go-go-related gene potassium channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src in cancer: deregulation and consequences for cell behaviour

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting EGFR resistance networks in head and neck cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligand-independent phosphorylation of Y869 (Y845) links mutant EGFR signaling to stat-mediated gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR mutations and EGFR tyrosine kinase inhibition in non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down-regulation of c-Src/EGFR-mediated signaling activation is involved in the honokiol-induced cell cycle arrest and apoptosis in MDA-MB-231 human breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle control of DNA replication.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of different combinations of gefitinib and irinotecan in lung cancer cell lines expressing wild or deletional EGFR.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src-dependent phosphorylation of the EGF receptor Tyr-845 mediates Stat-p21waf1 pathway in A431 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular functions regulated by Src family kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hexachlorobenzene triggers AhR translocation to the nucleus, c-Src activation and EGFR transactivation in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiologic classification of human papillomavirus types associated with cervical cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor: mechanisms of activation and signalling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down-regulation of phospho-non-receptor Src tyrosine kinases contributes to growth inhibition of cervical cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor (EGFR) signaling in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pp60c-Src inhibitor PP1 is non-competitive against ATP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The complexity of targeting EGFR signalling in cancer: from expression to turnover

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salivary phospholipid secretion in response to beta-adrenergic stimulation is mediated by Src kinase-dependent epidermal growth factor receptor transactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An in vitro chemosensitivity test for the screening of anti-cancer drugs in childhood leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src family kinase activity is required for Kit-mediated mitogen-activated protein (MAP) kinase activation, however loss of functional retinoblastoma protein makes MAP kinase activation unnecessary for growth of small cell lung cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src inhibitors: drugs for the treatment of osteoporosis, cancer or both?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-EGFR activation, anti-proliferative and pro-apoptotic effects of polyclonal antibodies induced by EGFR-based cancer vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of nuclear factor kappab activity by genistein is mediated via Notch-1 signaling pathway in pancreatic cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of resistance to the ABL tyrosine kinase inhibitor STI571 in BCR/ABL-transformed hematopoietic cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesion-dependent degranulation of neutrophils requires the Src family kinases Fgr and Hck

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MAP kinase stimulation by cAMP does not require RAP1 but SRC family kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of Lyn tyrosine kinase to the GM-CSF and IL-3 receptor common betac subunit and role of Src tyrosine kinases in DNA synthesis and anti-apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src inhibitor dasatinib inhibits growth of breast cancer cells by modulating EGFR signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and cellular effects of c-Src kinase-selective pyrido[2, 3-d]pyrimidine tyrosine kinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF receptor transactivation by urokinase receptor stimulus through a mechanism involving Src and matrix metalloproteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dasatinib: a potent SRC inhibitor in clinical development for the treatment of solid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Src trafficking and co-localization with the EGF receptor promotes EGF ligand-independent EGF receptor activation and signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SRC family kinases mediate epithelial Na+ channel inhibition by endothelin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11010-010-0632-1

1 reference

Europe PubMed Central

PubMed publication ID

13 May 2018

http://europepmc.org/abstract/MED/21052789

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 May 2018

http://europepmc.org/abstract/MED/21052789

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