(Q53321679)

13 May 2018

review article

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title

Heavy ion carcinogenesis and human space exploration. (English)

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13 May 2018

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1

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13 May 2018

author name string

Francis A Cucinotta

series ordinal

2

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13 May 2018

language of work or name

English

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publication date

2 May 2008

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13 May 2018

published in

Nature Reviews Cancer

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13 May 2018

volume

8

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13 May 2018

issue

6

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13 May 2018

page(s)

465-472

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13 May 2018

https://scigraph.springernature.com/pub.10.1038/nrc2391

exact match

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cites work

Chromosomal aberrations and SCEs as biomarkers of cancer risk

1 reference

Radiation-induced bystander effects--implications for cancer.

21 January 2018

1 reference

gamma-H2AX in bystander cells: not just a radiation-triggered event, a cellular response to stress mediated by intercellular communication

21 January 2018

1 reference

Amifostine reduces side effects and improves complete response rate during radiotherapy: results of a meta-analysis

21 January 2018

1 reference

A role for long-lived radicals (LLR) in radiation-induced mutation and persistent chromosomal instability: counteraction by ascorbate and RibCys but not DMSO.

21 January 2018

1 reference

Methylation changes in muscle and liver tissues of male and female mice exposed to acute and chronic low-dose X-ray-irradiation.

21 January 2018

1 reference

Geant4—a simulation toolkit

21 January 2018

1 reference

Space radiation effects and microgravity

21 January 2018

1 reference

Intensity-modulated radiation therapy, protons, and the risk of second cancers

21 January 2018

1 reference

Dietary factors and cancer mortality among atomic-bomb survivors

21 January 2018

1 reference

Cancer risk from exposure to galactic cosmic rays: implications for space exploration by human beings

21 January 2018

1 reference

31 March 2020

1 reference

Studies of mortality of atomic bomb survivors. Report 13: Solid cancer and noncancer disease mortality: 1950-1997.

31 March 2020

1 reference

Space radiation cancer risks and uncertainties for Mars missions.

31 March 2020

1 reference

Calculations of heavy-ion track structure

31 March 2020

1 reference

Model for radial dependence of frequency distributions for energy imparted in nanometer volumes from HZE particles

31 March 2020

1 reference

Initial events in the cellular effects of ionizing radiations: clustered damage in DNA.

31 March 2020

1 reference

Chromatin loops are responsible for higher counts of small DNA fragments induced by high-LET radiation, while chromosomal domains do not affect the fragment sizes

31 March 2020

1 reference

A review of dsb induction data for varying quality radiations

31 March 2020

1 reference

Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation

31 March 2020

1 reference

Dose-dependent misrejoining of radiation-induced DNA double-strand breaks in human fibroblasts: experimental and theoretical study for high- and low-LET radiation

31 March 2020

1 reference

Induction and quantification of gamma-H2AX foci following low and high LET-irradiation

31 March 2020

1 reference

Clusters of DNA double-strand breaks induced by different doses of nitrogen ions for various LETs: experimental measurements and theoretical analyses

31 March 2020

1 reference

Spectrum of complex DNA damages depends on the incident radiation

31 March 2020

1 reference

DNA double-strand break repair and development

31 March 2020

1 reference

The impact of a negligent G2/M checkpoint on genomic instability and cancer induction.

31 March 2020

1 reference

DNA double-strand break repair: all's well that ends well

31 March 2020

1 reference

The role of double-strand break repair — insights from human genetics

31 March 2020

1 reference

Imaging features that discriminate between foci induced by high- and low-LET radiation in human fibroblasts.

31 March 2020

1 reference

Immunofluorescence Detection of Clustered γ-H2AX Foci Induced by HZE-Particle Radiation

31 March 2020

1 reference

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

31 March 2020

1 reference

Artemis deficiency confers a DNA double-strand break repair defect and Artemis phosphorylation status is altered by DNA damage and cell cycle progression

31 March 2020

1 reference

DNA double-strand break and chromosomal rejoining defects with misrejoining in Nijmegen breakage syndrome cells

31 March 2020

1 reference

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

31 March 2020

1 reference

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4

31 March 2020

1 reference

DNA double-strand breaks are not sufficient to initiate recruitment of TRF2

31 March 2020

1 reference

Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks

31 March 2020

1 reference

Live cell imaging of heavy-ion-induced radiation responses by beamline microscopy.

31 March 2020

1 reference

Image-based modeling reveals dynamic redistribution of DNA damage into nuclear sub-domains

31 March 2020

1 reference

Gene expression changes in normal human skin fibroblasts induced by HZE-particle radiation

31 March 2020

1 reference

Spatio-temporal dynamics of chromatin containing DNA breaks

31 March 2020

1 reference

Positional stability of single double-strand breaks in mammalian cells

31 March 2020

1 reference

Perspectives on the formation of radiation-induced exchange aberrations

31 March 2020

1 reference

Biological effectiveness of accelerated particles for the induction of chromosome damage measured in metaphase and interphase human lymphocytes.

31 March 2020

1 reference

Persistence of chromosome aberrations in mice acutely exposed to 56Fe+26 ions

31 March 2020

1 reference

mFISH analysis of chromosomal damage in bone marrow cells collected from CBA/CaJ mice following whole body exposure to heavy ions (56Fe ions)

31 March 2020

1 reference

Karyotypes of human lymphocytes exposed to high-energy iron ions

31 March 2020

1 reference

Chromosome Intrachanges and Interchanges Detected by Multicolor Banding in Lymphocytes: Searching for Clastogen Signatures in the Human Genome

31 March 2020

1 reference

mBAND analysis of chromosomal aberrations in human epithelial cells exposed to low- and high-LET radiation

31 March 2020

1 reference

Chromosomes lacking telomeres are present in the progeny of human lymphocytes exposed to heavy ions.

31 March 2020

1 reference

Biomarkers of space radiation risk

31 March 2020

1 reference

Chromosomal aberrations and cancer risk: results of a cohort study from Central Europe

31 March 2020

1 reference

Chromosome aberrations in the blood lymphocytes of astronauts after space flight

31 March 2020

1 reference

Stability of chromosome aberrations in the blood lymphocytes of astronauts measured after space flight by FISH chromosome painting

31 March 2020

1 reference

Chromosome aberration dosimetry in cosmonauts after single or multiple space flights.

31 March 2020

1 reference

Tumorigenic potential of high-Z, high-LET charged-particle radiations

31 March 2020

1 reference

In vivo mammary tumourigenesis in the Sprague-Dawley rat and microdosimetric correlates.

31 March 2020

1 reference

Tumor induction in mice locally irradiated with carbon ions: a retrospective analysis

31 March 2020

1 reference

Transmission of chromosomal instability after plutonium α-particle irradiation

31 March 2020

1 reference

31 March 2020

Chromosomal instability.

1 reference

Genomic instability--the engine of tumorigenesis?

31 March 2020

1 reference

Radiation-induced genomic instability and its implications for radiation carcinogenesis

31 March 2020

1 reference

Genomic instability and the role of radiation quality

31 March 2020

1 reference

Ionizing radiation induces heritable disruption of epithelial cell interactions

31 March 2020

1 reference

High-LET radiation induces inflammation and persistent changes in markers of hippocampal neurogenesis

31 March 2020

1 reference

Radiation and the microenvironment - tumorigenesis and therapy

31 March 2020

1 reference

Solid cancer incidence in atomic bomb survivors: 1958-1998

31 March 2020

1 reference

The 15-country collaborative study of cancer risk among radiation workers in the nuclear industry: estimates of radiation-related cancer risks

31 March 2020

1 reference

Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells.

31 March 2020

1 reference

Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer

31 March 2020

1 reference

Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress

31 March 2020

1 reference

Ionizing radiation predisposes nonmalignant human mammary epithelial cells to undergo transforming growth factor beta induced epithelial to mesenchymal transition

31 March 2020

1 reference

Protection against ionizing radiation by antioxidant nutrients and phytochemicals

31 March 2020

1 reference

Improved tolerability of amifostine with rapid infusion and optimal patient preparation

31 March 2020

1 reference

31 March 2020

The antioxidant paradox

1 reference

Diet and cancer--the European Prospective Investigation into Cancer and Nutrition.

31 March 2020

1 reference

The nutritional status of astronauts is altered after long-term space flight aboard the International Space Station

31 March 2020

1 reference

Induction and prevention of carcinogenesis in rat skin exposed to space radiation.

31 March 2020

1 reference

Effects of dietary supplements on the space radiation-induced reduction in total antioxidant status in CBA mice

31 March 2020

1 reference

Countermeasures against space radiation induced oxidative stress in mice

31 March 2020

1 reference

Effects of age and diet on the heavy particle-induced disruption of operant responding produced by a ground-based model for exposure to cosmic rays

31 March 2020

1 reference

Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis

31 March 2020

1 reference

Individual variation of somatic gene mutability in relation to cancer susceptibility: prospective study on erythrocyte glycophorin a gene mutations of atomic bomb survivors

31 March 2020

1 reference

31 March 2020

1 reference

Cancer risks and mortality in heterozygous ATM mutation carriers

31 March 2020

1 reference

Atm heterozygous mice are more sensitive to radiation-induced cataracts than are their wild-type counterparts.

31 March 2020

1 reference

Mrad9 and atm haploinsufficiency enhance spontaneous and X-ray-induced cataractogenesis in mice

31 March 2020

1 reference

Chromosomal radiosensitivity in BRCA1 and BRCA2 mutation carriers.

31 March 2020

1 reference

A defect in DNA double strand break processing in cells from unaffected parents of retinoblastoma patients and other apparently normal humans.

31 March 2020

1 reference

Genetic predisposition for the development of radiation-associated meningioma: an epidemiological study

31 March 2020

1 reference

Cancer caused by x-rays--a random event?

31 March 2020

1 reference

The relative biological effectiveness of densely ionizing heavy-ion radiation for inducing ocular cataracts in wild type versus mice heterozygous for the ATM gene.

31 March 2020

1 reference

Issues in protection from galactic cosmic rays

31 March 2020

1 reference

Radiation exposure for human Mars exploration.

31 March 2020

1 reference

31 March 2020

1 reference

Benchmark studies of the effectiveness of structural and internal materials as radiation shielding for the international space station.

31 March 2020

1 reference

Cytogenetic effects of high-energy iron ions: dependence on shielding thickness and material.

31 March 2020

1 reference

Accelerator-based tests of radiation shielding properties of materials used in human space infrastructures.

31 March 2020

1 reference

Novel shielding materials for space and air travel.

31 March 2020

1 reference

Shielding space travelers

31 March 2020

1 reference

Shielding from cosmic radiation for interplanetary missions: Active and passive methods

31 March 2020

1 reference

Ground-based research with heavy ions for space radiation protection

31 March 2020

1 reference

Preparatory study of a ground-based space radiobiology program in Europe

31 March 2020

1 reference

Particle radiation therapy using proton and heavier ion beams

31 March 2020

1 reference

Mechanisms of therapy-related carcinogenesis

31 March 2020

1 reference

Heavy ion radiobiology for hadrontherapy and space radiation protection

31 March 2020

1 reference

Radiation risk and human space exploration

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRC2391

1 reference

13 May 2018

1 reference

13 May 2018