(Q53343723)

http://europepmc.org/abstract/MED/11069945

13 May 2018

title

Selective and protracted apoptosis in human primary neurons microinjected with active caspase-3, -6, -7, and -8 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773170&resulttype=core&format=json

12 May 2020

author name string

Y Zhang

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773170&resulttype=core&format=json

12 May 2020

C Goodyer

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773170&resulttype=core&format=json

12 May 2020

A LeBlanc

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773170&resulttype=core&format=json

12 May 2020

language of work or name

English

0 references

publication date

1 November 2000

1 reference

http://europepmc.org/abstract/MED/11069945

13 May 2018

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773170&resulttype=core&format=json

12 May 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773170&resulttype=core&format=json

12 May 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773170&resulttype=core&format=json

12 May 2020

page(s)

8384-8389

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773170&resulttype=core&format=json

Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death.

12 May 2020

cites work

1 reference

12 December 2020

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease.

1 reference

12 December 2020

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

1 reference

12 December 2020

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

1 reference

12 December 2020

Presenilins are processed by caspase-type proteases.

1 reference

12 December 2020

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

1 reference

12 December 2020

Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases.

1 reference

12 December 2020

Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease.

1 reference

12 December 2020

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

1 reference

12 December 2020

Caspase dependent DNA fragmentation might be associated with excitotoxicity in Alzheimer disease

1 reference

12 December 2020

Alternative, non-secretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8.

1 reference

12 December 2020

Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons

1 reference

12 December 2020

Increased production of 4 kDa amyloid beta peptide in serum deprived human primary neuron cultures: possible involvement of apoptosis

1 reference

12 December 2020

Involvement of a caspase-3-like cysteine protease in 1-methyl-4-phenylpyridinium-mediated apoptosis of cultured cerebellar granule neurons.

1 reference

12 December 2020

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

1 reference

12 December 2020

Activation of CPP32 during apoptosis of neurons and astrocytes

1 reference

12 December 2020

Differential requirement for caspase 9 in apoptotic pathways in vivo.

1 reference

12 December 2020

Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases.

1 reference

12 December 2020

Caspase knockouts: matters of life and death.

1 reference

12 December 2020

A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

1 reference

12 December 2020

Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus-mediated gene transfer.

1 reference

12 December 2020

Caspase structure, proteolytic substrates, and function during apoptotic cell death

1 reference

12 December 2020

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1 reference

12 December 2020

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

1 reference

12 December 2020

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

1 reference

12 December 2020

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

1 reference

12 December 2020

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

1 reference

12 December 2020

In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease.

1 reference

12 December 2020

Changes in caspase expression in Alzheimer's disease: comparison with development and aging.

1 reference

12 December 2020

Increased production of amyloid precursor protein provides a substrate for caspase-3 in dying motoneurons.

1 reference

12 December 2020

In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system

1 reference

12 December 2020

Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease

1 reference

12 December 2020

Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury.

1 reference

12 December 2020

Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases.

1 reference

12 December 2020

Alzheimer disease: DNA fragmentation indicates increased neuronal vulnerability, but not apoptosis.

1 reference

12 December 2020

Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease

1 reference

12 December 2020

10.1523/JNEUROSCI.20-22-08384.2000

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773170&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773170&resulttype=core&format=json

12 May 2020

1 reference