(Q35788051)

English

Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death.

scientific article published on November 1999

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10550301%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10550301%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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Alzheimer's disease

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apoptotic process

1 reference

based on heuristic

inferred from title

7

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Europe PubMed Central

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1 November 2019

Christine Stadelmann

1

1 reference

Europe PubMed Central

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1 November 2019

author name string

T L Deckwerth

2

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1 November 2019

A Srinivasan

3

1 reference

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1 November 2019

C Bancher

4

1 reference

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1 November 2019

W Brück

5

1 reference

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1 November 2019

K Jellinger

6

1 reference

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1 November 2019

language of work or name

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publication date

1 November 1999

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1 November 2019

The American Journal of Pathology

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1 November 2019

155

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1 November 2019

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10550301%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1459-1466

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10550301%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965460-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspases as treatment targets in stroke and neurodegenerative diseases

1 reference

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12 July 2018

Changes in caspase expression in Alzheimer's disease: comparison with development and aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Phosphorylation of presenilin-2 regulates its cleavage by caspases and retards progression of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Caspases: enemies within

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Homology between a human apoptosis specific protein and the product of APG5, a gene involved in autophagy in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Generation of anti-apoptotic presenilin-2 polypeptides by alternative transcription, proteolysis, and caspase-3 cleavage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Cell cycle markers in the hippocampus in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Abnormal expression of the cell cycle regulators P16 and CDK4 in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Changes of p53 in the brains of patients with Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Beta-amyloid induces apoptosis in human-derived neurotypic SH-SY5Y cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Mechanisms of neuronal death in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

In situ labeling of dying cortical neurons in normal aging and in Alzheimer's disease: correlations with senile plaques and disease progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Evidence for neuronal apoptosis in pontosubicular neuron necrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Cell division and the nervous system: regulating the cycle from neural differentiation to death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Fas antigen expression in brains of patients with Alzheimer-type dementia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Ponto-subicular lesions in perinatal anoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Morphology of the aging brain, human and animal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Granulovacuolar degeneration of hippocampal pyramidal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

A monoclonal antibody that recognizes a phosphorylated epitope in Alzheimer neurofibrillary tangles, neurofilaments and tau proteins immunostains granulovacuolar degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Developmental cell death: morphological diversity and multiple mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Sequestration of tau by granulovacuolar degeneration in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

Reexamination of granulovacuolar degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region

1 reference

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12 July 2018

Monoclonal antibodies with selective specificity for Alzheimer Tau are directed against phosphatase-sensitive epitopes

1 reference

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12 July 2018

Topographic distribution of neurofibrillary tangles and granulovacuolar degeneration in hippocampal cortex of aging and demented patients. A quantitative study

1 reference

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12 July 2018

Granulovacuolar degeneration in pyramidal cells of the hippocampus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

12 July 2018

In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system

1 reference

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Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice.

1 reference

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25 September 2018

Neuronal expression of cycline dependent kinase inhibitors of the INK4 family in Alzheimer's disease.

1 reference

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25 September 2018

Caspase dependent DNA fragmentation might be associated with excitotoxicity in Alzheimer disease

1 reference

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25 September 2018

Cathepsin B-mediated activation of the proinflammatory caspase-11.

1 reference

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25 September 2018

A suicide note from Alzheimer disease neurons?

1 reference

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25 September 2018

Increased production of amyloid precursor protein provides a substrate for caspase-3 in dying motoneurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

25 September 2018

Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

25 September 2018

Progressive neuronal DNA damage associated with neurofibrillary tangle formation in Alzheimer disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

25 September 2018

Alzheimer disease: DNA fragmentation indicates increased neuronal vulnerability, but not apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

25 September 2018

DNA damage distribution in the human brain as shown by in situ end labeling; area-specific differences in aging and Alzheimer disease in the absence of apoptotic morphology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

25 September 2018

Presenilins are processed by caspase-type proteases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

25 September 2018

Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

25 September 2018

Bax protein expression is increased in Alzheimer's brain: correlations with DNA damage, Bcl-2 expression, and brain pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

25 September 2018

DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

25 September 2018

Up-regulation of Bcl-2 is associated with neuronal DNA damage in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

25 September 2018

G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP.

1 reference

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25 September 2018

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

25 September 2018

Immunohistochemical evidence for apoptosis in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

25 September 2018

In situ evidence for DNA fragmentation in Huntington's disease striatum and Alzheimer's disease temporal lobes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

25 September 2018

Evidence for apoptotic cell death in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866960

25 September 2018

Apoptotic cell death induced by beta-amyloid 1-42 peptide is cell type dependent

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965460-0

7 January 2021

Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965460-0

7 January 2021

A study of apoptosis in normal and pathologic nervous tissue after in situ end-labeling of DNA strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965460-0

7 January 2021

Diagnosis of Alzheimer's disease

1 reference

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7 January 2021

Overexpression of a C-terminal fragment of presenilin 1 delays anti-Fas induced apoptosis in Jurkat cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965460-0

7 January 2021

Identification of caspases that cleave presenilin-1 and presenilin-2

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965460-0

7 January 2021

Activation of caspase-3-like protease by digitonin-treated lysosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965460-0

7 January 2021

Role of an acidic compartment in tumor-necrosis-factor-alpha-induced production of ceramide, activation of caspase-3 and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965460-0

7 January 2021

In vitro studies on subtypes and regulation of active cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965460-0

7 January 2021

Oligodendrocyte apoptosis mediated by caspase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10550301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis and Alzheimer's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10550301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/S0002-9440(10)65460-0

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10550301%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10550301%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10550301%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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