(Q53352506)

13 May 2018

title

Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer. (English)

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13 May 2018

author name string

Xuemei Zhang

1

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13 May 2018

Xiaoping Miao

2

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13 May 2018

Yongli Guo

3

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13 May 2018

Wen Tan

4

1 reference

13 May 2018

Yifeng Zhou

5

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13 May 2018

Tong Sun

6

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13 May 2018

Yonggang Wang

7

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13 May 2018

Dongxin Lin

8

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13 May 2018

publication date

1 January 2006

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13 May 2018

published in

Human Mutation

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13 May 2018

volume

27

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13 May 2018

issue

1

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13 May 2018

page(s)

110-117

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13 May 2018

Codon 72 polymorphism of the TP53 gene

cites work

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Gene-environment interaction and aetiology of cancer: what does it mean and how can we measure it?

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https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

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https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Inhibiting the p53-MDM2 interaction: an important target for cancer therapy

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https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

MDM2 gene amplification: a new independent factor of adverse prognosis in non-small cell lung cancer (NSCLC).

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Mdm2 overexpression and p14(ARF) inactivation are two mutually exclusive events in primary human lung tumors

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

MDM2 induces hyperplasia and premalignant lesions when expressed in the basal layer of the epidermis.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Tobacco smoke carcinogens and lung cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

MDM2 gene amplification and expression in non-small-cell lung cancer: immunohistochemical expression of its protein is a favourable prognostic marker in patients without p53 protein accumulation

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https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis

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https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

p53 codon 72 polymorphism and cervical neoplasia: a meta-analysis review

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https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Regulation of p53 stability by Mdm2

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https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

p53, the cellular gatekeeper for growth and division

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https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Sequence variations in the DNA repair gene XPD and risk of lung cancer in a Chinese population

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https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

TP53 polymorphisms and lung cancer risk: a systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

The MDM2 gene amplification database

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

p53 Website and analysis of p53 gene mutations in human cancer: Forging a link between epidemiology and carcinogenesis

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https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Assessing TP53 status in human tumours to evaluate clinical outcome

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Role of a p53 polymorphism in the development of human papillomavirus-associated cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Two polymorphic variants of wild-type p53 differ biochemically and biologically

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

An efficient procedure for genotyping single nucleotide polymorphisms.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20277

7 January 2021

Identifiers

DOI

10.1002/HUMU.20277

1 reference

13 May 2018

1 reference

13 May 2018