(Q53373955)

13 May 2018

title

Loss of Desmoglein Binding Is Not Sufficient for Keratinocyte Dissociation in Pemphigus. (English)

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13 May 2018

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2

Jens Waschke

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13 May 2018

author name string

Franziska Vielmuth

series ordinal

1

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13 May 2018

Volker Spindler

series ordinal

3

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13 May 2018

language of work or name

English

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publication date

19 August 2015

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13 May 2018

Journal of Investigative Dermatology

published in

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13 May 2018

volume

135

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13 May 2018

issue

12

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13 May 2018

page(s)

3068-3077

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13 May 2018

https://scigraph.springernature.com/pub.10.1038/jid.2015.324

exact match

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cites work

Desmoglein versus non-desmoglein signaling in pemphigus acantholysis: characterization of novel signaling pathways downstream of pemphigus vulgaris antigens

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12 December 2020

Desmocollin 3-mediated binding is crucial for keratinocyte cohesion and is impaired in pemphigus

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12 December 2020

The desmosome and pemphigus

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12 December 2020

The pathogenic role of autoantibodies in pemphigus vulgaris

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12 December 2020

Adducin is required for desmosomal cohesion in keratinocytes

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12 December 2020

Nano-scale dynamic recognition imaging on vascular endothelial cells

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12 December 2020

Desmosome assembly and cell-cell adhesion are membrane raft-dependent processes.

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12 December 2020

p38 MAPK Signaling in Pemphigus: Implications for Skin Autoimmunity

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12 December 2020

Dominant autoimmune epitopes recognized by pemphigus antibodies map to the N-terminal adhesive region of desmogleins

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12 December 2020

Atomic force microscopy identifies regions of distinct desmoglein 3 adhesive properties on living keratinocytes

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12 December 2020

An electron microscopic study of acantholysis in pemphigus vulgaris

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12 December 2020

IgG-induced clustering of desmogleins 1 and 3 in skin of patients with pemphigus fits with the desmoglein nonassembly depletion hypothesis

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12 December 2020

Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris

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12 December 2020

Interaction of membrane/lipid rafts with the cytoskeleton: impact on signaling and function: membrane/lipid rafts, mediators of cytoskeletal arrangement and cell signaling

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12 December 2020

Atomic force microscopy-based force spectroscopy--biological and biomedical applications

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12 December 2020

Remodeling of keratin-coupled cell adhesion complexes

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12 December 2020

The molecular architecture of cadherins in native epidermal desmosomes

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12 December 2020

Pemphigus vulgaris autoantibody profiling by proteomic technique

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12 December 2020

Imaging and force spectroscopy on desmoglein 1 using atomic force microscopy reveal multivalent Ca(2+)-dependent, low-affinity trans-interaction.

1 reference

12 December 2020

Induction of p38MAPK and HSP27 phosphorylation in pemphigus patient skin

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12 December 2020

Peptide-mediated desmoglein 3 crosslinking prevents pemphigus vulgaris autoantibody-induced skin blistering

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12 December 2020

Desmosome signaling. Inhibition of p38MAPK prevents pemphigus vulgaris IgG-induced cytoskeleton reorganization

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12 December 2020

Desmosomes and extradesmosomal adhesive signaling contacts in pemphigus

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12 December 2020

Pemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanism

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12 December 2020

Anti-desmoglein 3 (Dsg3) monoclonal antibodies deplete desmosomes of Dsg3 and differ in their Dsg3-depleting activities related to pathogenicity

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12 December 2020

Pemphigus vulgaris-IgG causes a rapid depletion of desmoglein 3 (Dsg3) from the Triton X-100 soluble pools, leading to the formation of Dsg3-depleted desmosomes in a human squamous carcinoma cell line, DJM-1 cells

1 reference

12 December 2020

MAPKAP kinase 2 (MK2)-dependent and -independent models of blister formation in pemphigus vulgaris

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12 December 2020

Pemphigus autoimmunity: hypotheses and realities

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12 December 2020

p38MAPK signaling and desmoglein-3 internalization are linked events in pemphigus acantholysis.

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12 December 2020

A desmoplakin point mutation with enhanced keratin association ameliorates pemphigus vulgaris autoantibody-mediated loss of cell cohesion

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12 December 2020

Pemphigus IgG causes skin splitting in the presence of both desmoglein 1 and desmoglein 3.

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12 December 2020

Continual assembly of half-desmosomal structures in the absence of cell contacts and their frustrated endocytosis: a coordinated Sisyphus cycle.

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12 December 2020

Mechanisms of mitochondrial damage in keratinocytes by pemphigus vulgaris antibodies

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12 December 2020

Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3

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12 December 2020

Inhibition of Rho A activity causes pemphigus skin blistering

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12 December 2020

Desmosome assembly and disassembly are membrane raft-dependent

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12 December 2020

Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface.

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12 December 2020

Desmoglein-2 interaction is crucial for cardiomyocyte cohesion and function

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12 December 2020

Actin reorganization contributes to loss of cell adhesion in pemphigus vulgaris

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12 December 2020

Desmoglein endocytosis and desmosome disassembly are coordinated responses to pemphigus autoantibodies

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12 December 2020

Pemphigus vulgaris IgG directly inhibit desmoglein 3-mediated transinteraction

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12 December 2020

Keratins in health and disease

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12 December 2020

Plakoglobin but not desmoplakin regulates keratinocyte cohesion via modulation of p38MAPK signaling

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12 December 2020

p38MAPK inhibition prevents disease in pemphigus vulgaris mice

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12 December 2020

Assembly pathway of desmoglein 3 to desmosomes and its perturbation by pemphigus vulgaris-IgG in cultured keratinocytes, as revealed by time-lapsed labeling immunoelectron microscopy

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12 December 2020

Investigation of human keratinocyte cell adhesion using atomic force microscopy

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12 December 2020

Detection and localization of single molecular recognition events using atomic force microscopy

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12 December 2020

Pemphigus foliaceus IgG causes dissociation of desmoglein 1-containing junctions without blocking desmoglein 1 transinteraction

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12 December 2020

The extent of desmoglein 3 depletion in pemphigus vulgaris is dependent on Ca(2+)-induced differentiation: a role in suprabasal epidermal skin splitting?

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12 December 2020

Identifiers

DOI

10.1038/JID.2015.324

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13 May 2018

PubMed ID

26288352

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13 May 2018