(Q53385083)

13 May 2018

title

Transformation of normal human cells in the absence of telomerase activation. (English)

1 reference

13 May 2018

author

Yvette R Seger

1

1 reference

13 May 2018

Roberta Maestro

Roberta Maestro

8

0 references

Claudio Doglioni

Claudio Doglioni

5

0 references

Maria A Blasco

María A Blasco

6

0 references

Gregory Hannon

7

Gregory J Hannon

1 reference

13 May 2018

author name string

Marta García-Cao

2

1 reference

13 May 2018

Sara Piccinin

3

1 reference

13 May 2018

Crocifissa Lo Cunsolo

4

1 reference

13 May 2018

publication date

1 November 2002

1 reference

13 May 2018

published in

Cancer Cell

1 reference

13 May 2018

volume

2

1 reference

13 May 2018

page(s)

401-413

1 reference

13 May 2018

issue

5

1 reference

13 May 2018

High telomerase activity in primary lung cancers: association with increased cell proliferation rates and advanced pathologic stage.

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

1 reference

7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Telomere dynamics and telomerase activity in in vitro immortalised human cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

E1A signaling to p53 involves the p19(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Telomere maintenance by recombination in human cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Telomerase activity correlates with histo-pathological factors in uterine endometrial carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

The p400 complex is an essential E1A transformation target

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Creation of human tumour cells with defined genetic elements

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Enumeration of the simian virus 40 early region elements necessary for human cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

MaRX: an approach to genetics in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Association of adenovirus early-region 1A proteins with cellular polypeptides

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Mediation of c-Myc-induced apoptosis by p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Disease states associated with telomerase deficiency appear earlier in mice with short telomeres

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Impaired germinal center reaction in mice with short telomeres.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Correlating telomerase activity levels with human neuroblastoma outcomes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Specific association of human telomerase activity with immortal cells and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Essential role of mouse telomerase in highly proliferative organs

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

p53 status and the efficacy of cancer therapy in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Telomeres and their control

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Loss of telomeric sites in the chromosomes of Mus musculus domesticus (Rodentia: Muridae) during Robertsonian rearrangements

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Suppression of tumor growth by senescence in virally transformed human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

When checkpoints fail

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Telomere dysfunction and evolution of intestinal carcinoma in mice and humans

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Senescence as a mode of tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Normal telomere length and chromosomal end capping in poly(ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

1 reference

7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Activated v-myc and v-ras oncogenes do not transform normal human lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Myc activates telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Signaling pathways in Ras-mediated tumorigenicity and metastasis.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Cellular targets for transformation by the adenovirus E1A proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

Modifications of a telomeric repeat amplification protocol (TRAP) result in increased reliability, linearity and sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900183-6

7 January 2021

10.1016/S1535-6108(02)00183-6

Identifiers

DOI

1 reference

13 May 2018

PubMed ID

12450795

1 reference

13 May 2018