(Q53391608)

13 May 2018

title

Tumour p53 mutations exhibit promoter selective dominance over wild type p53. (English)

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13 May 2018

author name string

Paola Monti

1

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13 May 2018

Paola Campomenosi

2

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13 May 2018

Yari Ciribilli

3

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13 May 2018

Raffaella Iannone

4

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13 May 2018

Alberto Inga

5

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13 May 2018

Angelo Abbondandolo

6

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13 May 2018

Michael A Resnick

7

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13 May 2018

Gilberto Fronza

8

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13 May 2018

language of work or name

English

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publication date

1 March 2002

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13 May 2018

published in

Oncogene

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13 May 2018

volume

21

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13 May 2018

issue

11

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13 May 2018

page(s)

1641-1648

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13 May 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1205250

exact match

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cites work

p53 mutants have selective dominant-negative effects on apoptosis but not growth arrest in human cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

Inhibition of HIF-1- and wild-type p53-stimulated transcription by codon Arg175 p53 mutants with selective loss of functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

Dominant-negative p53 mutations selected in yeast hit cancer hot spots

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

Human tumor-derived p53 proteins exhibit binding site selectivity and temperature sensitivity for transactivation in a yeast-based assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

Ultraviolet-light induced p53 mutational spectrum in yeast is indistinguishable from p53 mutations in human skin cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

Oncogenic forms of p53 inhibit p53-regulated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

Novel p53 mutants selected in BRCA-associated tumours which dissociate transformation suppression from other wild-type p53 functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

Structural aspects of the p53 protein in relation to gene evolution: a second look.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

Evolutionary conservation and somatic mutation hotspot maps of p53: correlation with p53 protein structural and functional features.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

7 January 2021

Identification of human p53 mutations with differential effects on the bax and p21 promoters using functional assays in yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

7 January 2021

Determining mutational fingerprints at the human p53 locus with a yeast functional assay: a new tool for molecular epidemiology

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

7 January 2021

Tumour associated mutants of p53 can inhibit transcriptional activity of p53 without heterooligomerization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

7 January 2021

Relationship between DNA methylation and mutational patterns induced by a sequence selective minor groove methylating agent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

7 January 2021

Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

7 January 2021

High frequency in esophageal cancers of p53 alterations inactivating the regulation of genes involved in cell cycle and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

7 January 2021

Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205250

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205250

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13 May 2018

Dimensions Publication ID

0 references

1 reference

13 May 2018