(Q53423951)

14 May 2018

title

Novel p53 mutants selected in BRCA-associated tumours which dissociate transformation suppression from other wild-type p53 functions. (English)

1 reference

14 May 2018

author name string

Smith PD

1

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14 May 2018

Crossland S

2

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14 May 2018

Parker G

3

1 reference

14 May 2018

Osin P

4

1 reference

14 May 2018

Brooks L

5

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14 May 2018

Waller J

6

1 reference

14 May 2018

Philp E

7

1 reference

14 May 2018

Crompton MR

8

1 reference

14 May 2018

Gusterson BA

9

1 reference

14 May 2018

Allday MJ

10

1 reference

14 May 2018

Crook T

11

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14 May 2018

language of work or name

English

0 references

publication date

1 April 1999

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14 May 2018

published in

Oncogene

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14 May 2018

volume

18

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14 May 2018

issue

15

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14 May 2018

page(s)

2451-2459

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14 May 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1202565

exact match

0 references

cites work

Double indemnity: p53, BRCA and cancer. p53 mutation partially rescues developmental arrest in Brca1 and Brca2 null mice, suggesting a role for familial breast cancer genes in DNA damage repair.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

Transcriptional activation by p53 correlates with suppression of growth but not transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

A transforming p53 mutant, which binds DNA, transactivates and induces apoptosis reveals a nuclear:cytoplasmic shuttling defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

Cancer-susceptibility genes. Gatekeepers and caretakers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

21 January 2018

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21 January 2018

p53: puzzle and paradigm

1 reference

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Regulation of p53 stability by Mdm2

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis.

21 January 2018

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Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells

21 January 2018

1 reference

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Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

21 January 2018

1 reference

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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

Involvement of Brca2 in DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

A model for p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

E1A signaling to p53 involves the p19(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

Brca2 is required for embryonic cellular proliferation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

Identification of the breast cancer susceptibility gene BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

p53 mutations in BRCA1-associated familial breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

7 January 2021

inferred from DOI database lookup

p53 mutation with frequent novel condons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

7 January 2021

inferred from DOI database lookup

Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202565

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.ONC.1202565

1 reference

14 May 2018

release_335vch4k7rhill66mqux3t7pqy

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/335vch4k7rhill66mqux3t7pqy

24 November 2022

mapped directly with Wikidata item

1 reference

14 May 2018