(Q53562093)

English

The major secreted cathepsin L1 protease of the liver fluke, Fasciola hepatica: a Leu-12 to Pro-12 replacement in the nonconserved C-terminal region of the prosegment prevents complete enzyme autoactivation and allows definition of the molecular eve

scientific article published on 2 April 2007

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scholarly article

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

The major secreted cathepsin L1 protease of the liver fluke, Fasciola hepatica: a Leu-12 to Pro-12 replacement in the nonconserved C-terminal region of the prosegment prevents complete enzyme autoactivation and allows definition of the molecular eve (English)

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

1 reference

based on heuristic

inferred from title

Fasciola hepatica

object named as

Fasciola hepatica

1 reference

based on heuristic

inferred from title

Sheila M Donnelly

2

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

author name string

Colin M Stack

1

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

Jonathan Lowther

3

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

Weibo Xu

4

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

Peter R Collins

5

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

Linda S Brinen

6

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

John P Dalton

7

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

language of work or name

0 references

publication date

2 April 2007

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

Journal of Biological Chemistry

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Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

282

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

22

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

16532-16543

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propetide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Fasciola hepatica cathepsin L cysteine proteinase suppresses Bordetella pertussis-specific interferon-gamma production in vivo.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Correlation of specific antibody titre and avidity with protection in cattle immunized against Fasciola hepatica.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Helminth vaccines: from mining genomic information for vaccine targets to systems used for protein expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Functions of Propeptide Parts in Cysteine Proteases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Lysosomal cysteine proteases (cathepsins): promising drug targets.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Protease pro region required for folding is a potent inhibitor of the mature enzyme.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Protein memory through altered folding mediated by intramolecular chaperones.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Role of the prosegment of Fasciola hepatica cathepsin L1 in folding of the catalytic domain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Autocatalytic processing of recombinant human procathepsin L. Contribution of both intermolecular and unimolecular events in the processing of procathepsin L in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Autocatalytic processing of recombinant human procathepsin B is a bimolecular process

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Surface activation of pro-cathepsin L

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Multi-step processing of procathepsin L in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Cathepsins and compartmentalization in antigen presentation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Cysteine proteinases mediate extracellular prohormone processing in the thyroid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Crystal structures of human procathepsin B at 3.2 and 3.3 Angstroms resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Crystal structure of the wild-type human procathepsin B at 2.5 A resolution reveals the native active site of a papain-like cysteine protease zymogen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

The alpha1/2 helical backbone of the prodomains defines the intrinsic inhibitory specificity in the cathepsin L-like cysteine protease subfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Autocatalytic activation of human cathepsin K.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Processing of the papain precursor. The ionization state of a conserved amino acid motif within the Pro region participates in the regulation of intramolecular processing.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Functional expression of Fasciola hepatica cathepsin L1 in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Purification and characterisation of a second cathepsin L proteinase secreted by the parasitic trematode Fasciola hepatica.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Isolation of a cDNA encoding Fasciola hepatica cathepsin L2 and functional expression in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Comparative protein modelling by satisfaction of spatial restraints

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Comparative protein structure modeling of genes and genomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Modeling of loops in protein structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Coot: model-building tools for molecular graphics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Expression of functional papain precursor in Saccharomyces cerevisiae: rapid screening of mutants.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Autocatalytic processing of pro-papaya proteinase IV is prevented by crowding of the active-site cleft

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Cysteine proteases of parasitic organisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Role of the tegument and gut in nutrient uptake by parasitic platyhelminths

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Thyroid functions of mouse cathepsins B, K, and L

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611501200

21 January 2018

Identifiers

10.1074/JBC.M611501200

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17403677

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