(Q53617590)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16779700%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Establishment and characterization of the transformants stably-expressing MDR1 derived from various animal species in LLC-PK1 (English)

1 reference

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25 December 2019

8

1 reference

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25 December 2019

author name string

Toshiyuki Takeuchi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16779700%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Sumie Yoshitomi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16779700%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Tomoaki Higuchi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16779700%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Keiko Ikemoto

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16779700%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Shin-ichi Niwa

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16779700%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Takuya Ebihara

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16779700%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Miki Katoh

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16779700%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Satoru Asahi

9

1 reference

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25 December 2019

publication date

21 June 2006

1 reference

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25 December 2019

published in

Pharmaceutical Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16779700%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

23

1 reference

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25 December 2019

issue

7

1 reference

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25 December 2019

page(s)

1460-1472

1 reference

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Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine [seecomments]

25 December 2019

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11095-006-0285-7

Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1).

21 January 2018

1 reference

12 December 2020

Biotransformation enzymes in two renal epithelial cell lines (LLC-PK1 and RK-L).

1 reference

12 December 2020

Comparison of oral absorption and bioavailablity of drugs between monkey and human

1 reference

12 December 2020

Endogenous expression of the renal high-affinity H+-peptide cotransporter in LLC-PK1 cells.

1 reference

12 December 2020

Inhibitory potencies of 1,4-dihydropyridine calcium antagonists to P-glycoprotein-mediated transport: comparison with the effects on CYP3A4.

1 reference

12 December 2020

In vitro substrate identification studies for p-glycoprotein-mediated transport: species difference and predictability of in vivo results

1 reference

12 December 2020

Transporter-mediated Drug Interactions

1 reference

12 December 2020

Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein

1 reference

12 December 2020

Species differences in the disposition of the CCR5 antagonist, UK-427,857, a new potential treatment for HIV.

1 reference

12 December 2020

Efflux ratio cannot assess P-glycoprotein-mediated attenuation of absorptive transport: asymmetric effect of P-glycoprotein on absorptive and secretory transport across Caco-2 cell monolayers

1 reference

12 December 2020

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

12 December 2020

Role of P-glycoprotein in pharmacokinetics: clinical implications

1 reference

12 December 2020

Human (MDR1) and mouse (mdr1, mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators.

1 reference

12 December 2020

Rapid induction of P-glycoprotein expression by high permeability compounds in colonic cells in vitro: a possible source of transporter mediated drug interactions?

1 reference

12 December 2020

Functional characterization of glycosylation-deficient human P-glycoprotein using a vaccinia virus expression system

1 reference

12 December 2020

Nonlinear oral pharmacokinetics of the alpha-antagonist 4-amino-5-(4-fluorophenyl)-6,7-dimethoxy-2-[4-(morpholinocarbonyl)-perhydro-1,4-diazepin-1-yl]quinoline in humans: use of preclinical data to rationalize clinical observations

1 reference

12 December 2020

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

1 reference

12 December 2020

Utility of Mdr1-gene deficient mice in assessing the impact of P-glycoprotein on pharmacokinetics and pharmacodynamics in drug discovery and development

1 reference

12 December 2020

Transport of tetraethylammonium by a kidney epithelial cell line (LLC-PK1)

1 reference

12 December 2020

Pharmacokinetics and interactions of a novel antagonist of chemokine receptor 5 (CCR5) with ritonavir in rats and monkeys: role of CYP3A and P-glycoprotein

1 reference

12 December 2020

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

1 reference

12 December 2020

The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

1 reference

12 December 2020

Mechanisms of gentamicin transport in kidney epithelial cell line (LLC-PK1)

1 reference

12 December 2020

Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation

1 reference

12 December 2020

The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions

1 reference

12 December 2020

Transepithelial transport in cell culture:d-Glucose transport by a pig kidney cell line (LLC-PK1)

1 reference

12 December 2020

The role of P-glycoprotein in limiting intestinal regional absorption of digoxin in rats

1 reference

12 December 2020

Transport of cyclosporin A in kidney epithelial cell line (LLC-PK1).

1 reference

12 December 2020

Endogenous drug transporters in in vitro and in vivo models for the prediction of drug disposition in man.

1 reference

12 December 2020

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

12 December 2020

The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability

1 reference

12 December 2020

N-glycosylation and deletion mutants of the human MDR1 P-glycoprotein

1 reference

12 December 2020

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

1 reference

12 December 2020

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

12 December 2020

Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone

1 reference

12 December 2020

Transport of organic cations by kidney epithelial cell line LLC-PK1.

1 reference

12 December 2020