(Q53617978)

16 May 2018

title

miR-148a promotes plasma cell differentiation and targets the germinal center transcription factors Mitf and Bach2. (English)

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16 May 2018

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10

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16 May 2018

Hans-Martin Jäck

18

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16 May 2018

Andreas Radbruch

16

object named as

Andreas Radbruch

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16 May 2018

author name string

Martina Porstner

1

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16 May 2018

Rebecca Winkelmann

2

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16 May 2018

Patrick Daum

3

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16 May 2018

Julia Schmid

4

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16 May 2018

Katharina Pracht

5

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16 May 2018

Joana Côrte-Real

6

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16 May 2018

Sandra Schreiber

7

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16 May 2018

Claudia Haftmann

8

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16 May 2018

Andreas Brandl

9

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16 May 2018

Kolja Gelse

11

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Manuela Hauke

12

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16 May 2018

Ina Wirries

13

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16 May 2018

Markus Zwick

14

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16 May 2018

Edith Roth

15

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16 May 2018

Jürgen Wittmann

17

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16 May 2018

language of work or name

English

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publication date

12 March 2015

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16 May 2018

European Journal of Immunology

published in

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16 May 2018

volume

45

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16 May 2018

issue

4

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16 May 2018

page(s)

1206-1215

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16 May 2018

Regulation of plasma-cell development

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Germinal center selection and the development of memory B and plasma cells

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The genetic network controlling plasma cell differentiation

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Gene interaction network regulates plasma cell differentiation.

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

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Disruption of the Bcl6 gene results in an impaired germinal center formation

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The transcriptional programme of antibody class switching involves the repressor Bach2.

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Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch

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Active inhibition of plasma cell development in resting B cells by microphthalmia-associated transcription factor

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Regulation of the plasma cell transcription factor Blimp-1 gene by Bach2 and Bcl6.

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MicroRNA regulation of the germinal center response

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MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1.

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miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.

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The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes.

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Plasmacytic transcription factor Blimp-1 is repressed by Bach2 in B cells

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Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination.

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MicroRNA 125b inhibition of B cell differentiation in germinal centers

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Contribution of microRNA 24-3p and Erk1/2 to interleukin-6-mediated plasma cell survival

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miR-181b negatively regulates activation-induced cytidine deaminase in B cells

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Regulation of the germinal center response by microRNA-155

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BCL6 positively regulates AID and germinal center gene expression via repression of miR-155.

21 January 2018

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microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma

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21 January 2018

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miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors.

21 January 2018

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Regulation of microRNA expression and abundance during lymphopoiesis

21 January 2018

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A facile method to increase titers of miRNA-encoding retroviruses by inhibition of the RNaseIII enzyme Drosha.

21 January 2018

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Swiprosin-1/EFhd2 limits germinal center responses and humoral type 2 immunity

21 January 2018

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Regulation of immunoglobulin gene expression in normal lymphocytes. II. Mechanisms of down-regulation of immunoglobulin secretion after engagement of the B cell antigen receptor

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444637

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/EJI.201444637

1 reference

16 May 2018

1 reference

16 May 2018