(Q53659116)

English

Contrarily to whey and high protein diets, dietary free leucine supplementation cannot reverse the lack of recovery of muscle mass after prolonged immobilization during ageing.

scientific article published on 20 February 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Contrarily to whey and high protein diets, dietary free leucine supplementation cannot reverse the lack of recovery of muscle mass after prolonged immobilization during ageing (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

5

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Dominique Dardevet

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

author name string

Hugues Magne

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Isabelle Savary-Auzeloux

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Carole Migné

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Marie-Agnès Peyron

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

language of work or name

0 references

publication date

20 February 2012

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Journal of Physiology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

590

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

2035-2049

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Skeletal muscle protein metabolism in the elderly: Interventions to counteract the 'anabolic resistance' of ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Long-term effects of leucine supplementation on body composition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Leucine attenuates skeletal muscle wasting via inhibition of ubiquitin ligases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Protecting muscle mass and function in older adults during bed rest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Reduction of low grade inflammation restores blunting of postprandial muscle anabolism and limits sarcopenia in old rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Alterations of protein turnover underlying disuse atrophy in human skeletal muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Presence of low-grade inflammation impaired postprandial stimulation of muscle protein synthesis in old rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Differential stimulation of myofibrillar and sarcoplasmic protein synthesis with protein ingestion at rest and after resistance exercise

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Antioxidant supplementation restores defective leucine stimulation of protein synthesis in skeletal muscle from old rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Positive energy balance is associated with accelerated muscle atrophy and increased erythrocyte glutathione turnover during 5 wk of bed rest.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

The ubiquitin-proteasome and the mitochondria-associated apoptotic pathways are sequentially downregulated during recovery after immobilization-induced muscle atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Protocol for high-resolution separation of rodent myosin heavy chain isoforms in a mini-gel electrophoresis system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

The temporal responses of protein synthesis, gene expression and cell signalling in human quadriceps muscle and patellar tendon to disuse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Influence of concurrent exercise or nutrition countermeasures on thigh and calf muscle size and function during 60 days of bed rest in women.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Increased availability of leucine with leucine-rich whey proteins improves postprandial muscle protein synthesis in aging rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

A leucine-supplemented diet restores the defective postprandial inhibition of proteasome-dependent proteolysis in aged rat skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Hindlimb casting decreases muscle mass in part by proteasome-dependent proteolysis but independent of protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Oral leucine administration stimulates protein synthesis in rat skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

The effect of hindlimb immobilization on acid phosphatase, metalloproteinases and nuclear factor-kappaB in muscles of young and old rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Combined ingestion of protein and free leucine with carbohydrate increases postexercise muscle protein synthesis in vivo in male subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Leucine regulates translation initiation in rat skeletal muscle via enhanced eIF4G phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Amino acid ingestion improves muscle protein synthesis in the young and elderly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Human muscle protein synthesis is modulated by extracellular, not intramuscular amino acid availability: a dose-response study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Hindlimb unloading increases oxidative stress and disrupts antioxidant capacity in skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

The rate of protein digestion affects protein gain differently during aging in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Tissue-specific effects of chronic dietary leucine and norleucine supplementation on protein synthesis in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Chemotherapy inhibits skeletal muscle ubiquitin-proteasome-dependent proteolysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

The digestion rate of protein is an independent regulating factor of postprandial protein retention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Feeding stimulates protein synthesis in muscle and liver of neonatal pigs through an mTOR-dependent process.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Orally administered leucine stimulates protein synthesis in skeletal muscle of postabsorptive rats in association with increased eIF4F formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Muscle mass and strength: relation to function in population studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Prolonged bed rest decreases skeletal muscle and whole body protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Coordinate activation of lysosomal, Ca 2+-activated and ATP-ubiquitin-dependent proteinases in the unweighted rat soleus muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Muscle and liver protein synthesis adapt efficiently to food deprivation and refeeding in 12-month-old rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Sensitivity and protein turnover response to glucocorticoids are different in skeletal muscle from adult and old rats. Lack of regulation of the ubiquitin-proteasome proteolytic pathway in aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Effect of limb immobilization on skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Degeneration of different types of skeletal muscle fibres. II. Immobilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Muscle fibre size and number following immobilisation atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Role of leucine and other amino acids in regulating protein metabolism in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Leucine. A possible regulator of protein turnover in muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

The influence of immobilization and stretch on protein turnover of rat skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

25 August 2018

Reporting ethical matters in the Journal of Physiology: standards and advice

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.226266

21 January 2018

TNF-alpha impairs heart and skeletal muscle protein synthesis by altering translation initiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573319

30 November 2018

Oxidative stress during recovery from muscle atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of protein intake on protein synthesis and fiber distribution in the unweighted soleus muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leucine-supplemented meal feeding for ten days beneficially affects postprandial muscle protein synthesis in old rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of aging on human skeletal muscle after immobilization and retraining

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IGF-I restores satellite cell proliferative potential in immobilized old skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of passive stretching on the immobilized soleus muscle fiber morphology

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of proteolysis during reloading of the unweighted soleus muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of inactivity and passive stretch on protein turnover in phasic and postural rat muscles

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered response of protein synthesis to nutritional state and endurance training in old rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decrease in human quadriceps muscle protein turnover consequent upon leg immobilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capacity for recovery and possible mechanisms in immobilization atrophy of young and old animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of 10 days of bed rest on skeletal muscle in healthy older adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lower limb skeletal muscle function after 6 wk of bed rest

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of the protein wasting associated with bed rest by branched-chain amino acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selected Contribution: Identification of differentially expressed genes between young and old rat soleus muscle during recovery from immobilization-induced atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitin-proteasome-dependent proteolytic activity remains elevated after zymosan-induced sepsis in rats while muscle mass recovers

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of muscle recovery after immobilization in old rats does not result from a defect in normalization of the ubiquitin-proteasome and the caspase-dependent apoptotic pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of in vitro rat muscle protein synthesis by leucine decreases with age

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postprandial stimulation of muscle protein synthesis in old rats can be restored by a leucine-supplemented meal

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leucine supplementation enhances skeletal muscle recovery in rats following exercise

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Splanchnic and whole-body leucine kinetics in young and elderly men

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral administration of leucine stimulates ribosomal protein mRNA translation but not global rates of protein synthesis in the liver of rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1113/JPHYSIOL.2011.226266

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351629%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

ResearchGate publication ID

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