(Q53898296)

22 May 2018

title

Understanding of the Hsp90 molecular chaperone reaches new heights. (English)

1 reference

22 May 2018

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2

Len Neckers

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22 May 2018

author name string

Cara K Vaughan

series ordinal

1

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22 May 2018

Peter W Piper

series ordinal

3

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22 May 2018

publication date

1 December 2010

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22 May 2018

Nature Structural & Molecular Biology

published in

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22 May 2018

volume

17

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22 May 2018

issue

12

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22 May 2018

page(s)

1400-1404

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22 May 2018

https://scigraph.springernature.com/pub.10.1038/nsmb1210-1400

exact match

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cites work

Asymmetric Activation of the Hsp90 Dimer by Its Cochaperone Aha1

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Structural Basis for Assembly of Hsp90-Sgt1-CHORD Protein Complexes: Implications for Chaperoning of NLR Innate Immunity Receptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Dynamics of heat shock protein 90 C-terminal dimerization is an important part of its conformational cycle

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

ATP binding to Hsp90 is sufficient for effective chaperoning of p53 protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Regulation of the cellular heat shock response in Caenorhabditis elegans by thermosensory neurons

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Hsp90 isoforms: functions, expression and clinical importance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

GCUNC45 is the first Hsp90 co-chaperone to show alpha/beta isoform specificity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

The non-canonical Hop protein from Caenorhabditis elegans exerts essential functions and forms binary complexes with either Hsc70 or Hsp90.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Extending healthy life span--from yeast to humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

The chaperone activity of GRP94 toward insulin-like growth factor II is necessary for the stress response to serum deprivation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

An essential role for ATP binding and hydrolysis in the chaperone activity of GRP94 in cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Trithorax requires Hsp90 for maintenance of active chromatin at sites of gene expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Hsp90 as a capacitor of phenotypic variation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Evolutionary constraints on chaperone-mediated folding provide an antiviral approach refractory to development of drug resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Targeting the dynamic HSP90 complex in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Update on Hsp90 inhibitors in clinical trial.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Targeting HSP70: the second potentially druggable heat shock protein and molecular chaperone?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Structural basis of the radicicol resistance displayed by a fungal hsp90

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

A simple yeast-based system for analyzing inhibitor resistance in the human cancer drug targets Hsp90alpha/beta

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Stress-inducible responses and heat shock proteins: new pharmacologic targets for cytoprotection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Neuroprotective activity and evaluation of Hsp90 inhibitors in an immortalized neuronal cell line

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Molecular recognition and drug-lead identification: what can molecular simulations tell us?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Heat shock protein 90 as a drug target against protozoan infections: biochemical characterization of HSP90 from Plasmodium falciparum and Trypanosoma evansi and evaluation of its inhibitor as a candidate drug

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

A repurposing strategy identifies novel synergistic inhibitors of Plasmodium falciparum heat shock protein 90.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB1210-1400

Targeting heat shock protein 72 enhances Hsp90 inhibitor-induced apoptosis in myeloma.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21127511

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Extracellular roles for the molecular chaperone, hsp90.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21127511

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB1210-1400

1 reference

22 May 2018

PubMed ID

21127511

1 reference

22 May 2018