(Q53959131)

23 May 2018

title

Characterization of a human alpha1-antitrypsin variant that is as stable as ovalbumin. (English)

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23 May 2018

author name string

Lee KN

1

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23 May 2018

Im H

2

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23 May 2018

Kang SW

3

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23 May 2018

Yu MH

4

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23 May 2018

language of work or name

English

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publication date

1 January 1998

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23 May 2018

Journal of Biological Chemistry

published in

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23 May 2018

volume

273

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23 May 2018

issue

5

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23 May 2018

page(s)

2509-2516

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23 May 2018

Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function

21 January 2018

1 reference

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Structural basis of latency in plasminogen activator inhibitor-1

21 January 2018

1 reference

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Crystal structure of plakalbumin, a proteolytically nicked form of ovalbumin. Its relationship to the structure of cleaved alpha-1-proteinase inhibitor

21 January 2018

1 reference

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Structural basis for serpin inhibitor activity

21 January 2018

1 reference

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Divining the serpin inhibition mechanism: a suicide substrate 'springe'?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

The role of conformational change in serpin structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

The inhibition mechanism of serpins. Evidence that the mobile reactive center loop is cleaved in the native protease-inhibitor complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

The Z type variation of human alpha 1-antitrypsin causes a protein folding defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Spectroscopic Determination of Tryptophan and Tyrosine in Proteins*

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Rapid and efficient site-specific mutagenesis without phenotypic selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Effects of mutations in the hinge region of serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Kinetics of the inhibition of thrombin by hirudin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Structural transition of alpha 1-antitrypsin by a peptide sequentially similar to beta-strand s4A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Reversible unfolding of the major fraction of ovalbumin by guanidine hydrochloride.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Crystal structure of ovalbumin as a model for the reactive centre of serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Synthesis of pppGpN typs dinucleotide derivatives: the 5′ end sequence of some RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

On-pathway versus off-pathway folding intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Alpha 1-proteinase inhibitor variant T345R. Influence of P14 residue on substrate and inhibitory pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Proteolytically cleaved mutant antithrombin-Hamilton has high stability to denaturation characteristic of wild type inhibitor serpins

21 January 2018

1 reference

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Mechanisms contributing to the conformational and functional flexibility of plasminogen activator inhibitor-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Structural change in alpha-chymotrypsin induced by complexation with alpha 1-antichymotrypsin as seen by enhanced sensitivity to proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Serpin conformational change in ovalbumin. Enhanced reactive center loop insertion through hinge region mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Structural aspects of serpin inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Mechanism of heparin activation of antithrombin. Evidence for reactive center loop preinsertion with expulsion upon heparin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Substrate behavior of plasminogen activator inhibitor-1 is not associated with a lack of insertion of the reactive site loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Inhibitory activity and conformational transition of alpha1-proteinase inhibitor variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

21 January 2018

Up the kinetic pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Type-1 inhibitor of plasminogen activators. Distinction between latent, activated and reactive centre-cleaved forms with thermal stability and monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Modeling of serpin-protease complexes: antithrombin-thrombin, alpha 1-antitrypsin (358Met-->Arg)-thrombin, alpha 1-antitrypsin (358Met-->Arg)-trypsin, and antitrypsin-elastase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Probing the native strain iin alpha1-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Serpin-protease complexes are trapped as stable acyl-enzyme intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Preparation and characterization of latent alpha 1-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Sodium dodecyl sulfate-stable complexes between serpins and active or inactive proteinases contain the region COOH-terminal to the reactive site loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

The synthesis and analytical use of a highly sensitive and convenient substrate of elastase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Conversion of alpha 1-antichymotrypsin into a human neutrophil elastase inhibitor: demonstration of variants with different association rate constants, stoichiometries of inhibition, and complex stabilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Effects of glycosylation on the folding and stability of human, recombinant and cleaved alpha 1-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Crystal structure of an uncleaved serpin reveals the conformation of an inhibitory reactive loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Evidence for a three-state model of protein folding from kinetic analysis of ubiquitin variants with altered core residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Arginine substitutions in the hinge region of antichymotrypsin affect serpin beta-sheet rearrangement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Mechanism of serpin action: evidence that C1 inhibitor functions as a suicide substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Trypsin complexed with alpha 1-proteinase inhibitor has an increased structural flexibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

Distortion of the active site of chymotrypsin complexed with a serpin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.5.2509

21 January 2018

Identifiers

DOI

10.1074/JBC.273.5.2509

1 reference

23 May 2018

1 reference

23 May 2018