(Q53959858)

23 May 2018

title

Role for the double-stranded RNA activated protein kinase PKR in E2F-1-induced apoptosis. (English)

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23 May 2018

10

Kelly K Hunt

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23 May 2018

Stephen Swisher

9

object named as

Stephen G Swisher

1 reference

23 May 2018

Mien-Chie Hung

8

object named as

Mien-Chie Hung

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23 May 2018

Weiya Xia

5

object named as

Weiya Xia

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23 May 2018

author name string

Stephan A Vorburger

1

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23 May 2018

Abujiang Pataer

2

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23 May 2018

Kazumi Yoshida

3

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23 May 2018

Glen N Barber

4

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23 May 2018

Paul Chiao

6

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23 May 2018

Lee M Ellis

7

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23 May 2018

language of work or name

English

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publication date

1 September 2002

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23 May 2018

published in

Oncogene

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23 May 2018

volume

21

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23 May 2018

issue

41

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23 May 2018

page(s)

6278-6288

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23 May 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1205761

exact match

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cites work

Depletion of intracellular Ca2+ stores, phosphorylation of eIF2alpha, and sustained inhibition of translation initiation mediate the anticancer effects of clotrimazole

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A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

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Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling

21 January 2018

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p14ARF links the tumour suppressors RB and p53.

21 January 2018

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Double-stranded RNA-dependent protein kinase is not required for double-stranded RNA-induced nitric oxide synthase expression or nuclear factor-kappaB activation by islets

21 January 2018

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Characterization of the solution complex between the interferon-induced, double-stranded RNA-activated protein kinase and HIV-I trans-activating region RNA.

21 January 2018

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The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro

21 January 2018

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Distinct roles for E2F proteins in cell growth control and apoptosis

21 January 2018

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Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast

21 January 2018

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DNA-binding and trans-activation properties of Drosophila E2F and DP proteins

21 January 2018

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The catalytic activity of dsRNA-dependent protein kinase, PKR, is required for NF-kappaB activation.

21 January 2018

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Expression of the double-stranded RNA-dependent protein kinase (p68) in squamous cell carcinoma of the head and neck region

21 January 2018

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E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

21 January 2018

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Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 January 2018

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Activation of the I kappa B alpha kinase (IKK) complex by double-stranded RNA-binding defective and catalytic inactive mutants of the interferon-inducible protein kinase PKR.

21 January 2018

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RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling

21 January 2018

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PKR, apoptosis and cancer

21 January 2018

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The war against the interferon-induced dsRNA-activated protein kinase: can viruses win?

21 January 2018

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Induction of TNF-sensitive cellular phenotype by c-Myc involves p53 and impaired NF-kappaB activation

21 January 2018

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Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase

21 January 2018

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Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

21 January 2018

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Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB

21 January 2018

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E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

21 January 2018

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Platelet-derived growth factor signal transduction through the interferon-inducible kinase PKR. Immediate early gene induction

21 January 2018

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Initiation of protein synthesis in eukaryotic cells

21 January 2018

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PACT, a stress-modulated cellular activator of interferon-induced double-stranded RNA-activated protein kinase, PKR.

21 January 2018

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Requirement of PKR dimerization mediated by specific hydrophobic residues for its activation by double-stranded RNA and its antigrowth effects in yeast

21 January 2018

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DRBP76, a double-stranded RNA-binding nuclear protein, is phosphorylated by the interferon-induced protein kinase, PKR

21 January 2018

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Early events in signalling by interferons.

21 January 2018

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Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

21 January 2018

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E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways

21 January 2018

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Activation of the double-stranded RNA-regulated protein kinase by depletion of endoplasmic reticular calcium stores

21 January 2018

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Bcl-3 expression promotes cell survival following interleukin-4 deprivation and is controlled by AP1 and AP1-like transcription factors

21 January 2018

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Role of the RNA-dependent protein kinase in the regulated expression of genes in transfected cells

21 January 2018

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Mechanism of interferon action: structure of the mouse PKR gene encoding the interferon-inducible RNA-dependent protein kinase

21 January 2018

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Mouse interferon-inducible RNA-dependent protein kinase Pkr gene: cloning and sequence of the 5'-flanking region and functional identification of the minimal inducible promoter

21 January 2018

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E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo

21 January 2018

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2-Aminopurine selectively blocks the transcriptional activation of cellular genes by virus, double-stranded RNA and interferons in human cells

21 January 2018

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Enhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKR

21 January 2018

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Tumor suppressor p53 as a component of the tumor necrosis factor-induced, protein kinase PKR-mediated apoptotic pathway in human promonocytic U937 cells

21 January 2018

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An essential role for the interferon-inducible, double-stranded RNA-activated protein kinase PKR in the tumor necrosis factor-induced apoptosis in U937 cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205761

Mutational analysis of p73 and p53 in human cancer cell lines.

21 January 2018

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Cell cycle regulation of the double stranded RNA activated protein kinase, PKR

21 January 2018

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The cellular effects of E2F overexpression

21 January 2018

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7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205761

7 January 2021

The binding of double-stranded RNA and adenovirus VAI RNA to the interferon-induced protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205761

7 January 2021

The double-stranded RNA-dependent protein kinase is also activated by heparin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205761

7 January 2021

Double-stranded RNA-dependent protein kinase and 2-5A system are both activated in interferon-treated, encephalomyocarditis virus-infected HeLa cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205761

7 January 2021

Abnormal levels and minimal activity of the dsRNA-activated protein kinase, PKR, in breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205761

7 January 2021

Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205761

7 January 2021

2-Aminopurine selectively inhibits the induction of beta-interferon, c-fos, and c-myc gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205761

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205761

1 reference

23 May 2018

Dimensions Publication ID

0 references

1 reference

23 May 2018