Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q53994091)
Watch
English
Can an optimization/scoring procedure in ligand-protein docking be employed to probe drug-resistant mutations in proteins?
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11552685
retrieved
23 May 2018
reference URL
http://europepmc.org/abstract/MED/11552685
title
Can an optimization/scoring procedure in ligand-protein docking be employed to probe drug-resistant mutations in proteins?
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11552685
retrieved
23 May 2018
reference URL
http://europepmc.org/abstract/MED/11552685
author name string
Chen YZ
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11552685
retrieved
23 May 2018
reference URL
http://europepmc.org/abstract/MED/11552685
Gu XL
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11552685
retrieved
23 May 2018
reference URL
http://europepmc.org/abstract/MED/11552685
Cao ZW
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11552685
retrieved
23 May 2018
reference URL
http://europepmc.org/abstract/MED/11552685
publication date
1 January 2001
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11552685
retrieved
23 May 2018
reference URL
http://europepmc.org/abstract/MED/11552685
published in
Journal of Molecular Graphics & Modelling
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11552685
retrieved
23 May 2018
reference URL
http://europepmc.org/abstract/MED/11552685
volume
19
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11552685
retrieved
23 May 2018
reference URL
http://europepmc.org/abstract/MED/11552685
issue
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11552685
retrieved
23 May 2018
reference URL
http://europepmc.org/abstract/MED/11552685
page(s)
560-570
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11552685
retrieved
23 May 2018
reference URL
http://europepmc.org/abstract/MED/11552685
cites work
Structure-based strategies for drug design and discovery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A fast flexible docking method using an incremental construction algorithm.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development and validation of a genetic algorithm for flexible docking
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Consensus scoring: A method for obtaining improved hit rates from docking databases of three-dimensional structures into proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A general and fast scoring function for protein-ligand interactions: a simplified potential approach.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding of an antiviral agent to a sensitive and a resistant human rhinovirus. Computer simulation studies with sampling of amino acid side-chain conformations. II. Calculation of free-energy differences by thermodynamic integration.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular mechanisms of drug resistance in Mycobacterium tuberculosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural mechanisms of HIV drug resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular basis of HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with cyclic urea inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance to HIV protease inhibitors: a comparison of enzyme inhibition and antiviral potency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Solvation effects are responsible for the reduced inhibitor affinity of some HIV-1 PR mutants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new method for predicting binding affinity in computer-aided drug design
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding affinities for sulfonamide inhibitors with human thrombin using Monte Carlo simulations with a linear response method
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of a series of phenylalanine 57 mutants of the adipocyte lipid-binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance and cross-resistance with saquinavir and other HIV protease inhibitors: theory and practice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV resistance to reverse transcriptase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel binding mode of highly potent HIV-proteinase inhibitors incorporating the (R)-hydroxyethylamine isostere
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An orally bioavailable HIV-1 protease inhibitor containing an imidazole-derived peptide bond replacement: crystallographic and pharmacokinetic analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structures of complexes of a peptidic inhibitor with wild-type and two mutant HIV-1 proteases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High resolution structures of HIV-1 RT from four RT-inhibitor complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Internal motions of antibody molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Premelting thermal fluctuational interbase hydrogen-bond disrupted states of a B-DNA guanine-cytosine base pair: significance for amino and imino proton exchange
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of a minor groove spine of hydration in stabilizing poly(dA). poly(dT) against fuctuational interbase H-bond disruption in the premelting temperature regime
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Solvation energy in protein folding and binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Atomic solvation parameters applied to molecular dynamics of proteins in solution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational anatomy of an HIV-1 protease variant conferring cross-resistance to protease inhibitors in clinical trials. Compensatory modulations of binding and activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
pi-Stacking interactions. Alive and well in proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure-based thermodynamic analysis of HIV-1 protease inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prediction of Binding Affinities for TIBO Inhibitors of HIV-1 Reverse Transcriptase Using Monte Carlo Simulations in a Linear Response Method
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dominant forces in protein folding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of point mutations on the kinetics and the inhibition of human immunodeficiency virus type 1 protease: relationship to drug resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1093-3263%2801%2900091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1093-3263(01)00091-2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11552685
retrieved
23 May 2018
reference URL
http://europepmc.org/abstract/MED/11552685
PubMed publication ID
11552685
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11552685
retrieved
23 May 2018
reference URL
http://europepmc.org/abstract/MED/11552685
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit