(Q54224159)

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Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-κB DNA-binding activity.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732239%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-κB DNA-binding activity (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732239%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

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renal cell carcinoma

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based on heuristic

inferred from title

9

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4 March 2020

author name string

Yung-Wei Lin

1

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4 March 2020

Liang-Ming Lee

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732239%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Wei-Jiunn Lee

3

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4 March 2020

Chih-Ying Chu

4

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4 March 2020

Peng Tan

5

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4 March 2020

Yi-Chieh Yang

6

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4 March 2020

Wei-Yu Chen

7

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4 March 2020

Shun-Fa Yang

8

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4 March 2020

Ming-Hsien Chien

10

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4 March 2020

publication date

3 February 2016

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Europe PubMed Central

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4 March 2020

Journal of Pineal Research

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4 March 2020

60

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4 March 2020

3

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4 March 2020

277-290

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4 March 2020

Cancer statistics, 2010

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Risk group assessment and clinical outcome algorithm to predict the natural history of patients with surgically resected renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Renal-Cell Carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Cancer invasion and metastases

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

The basement membrane matrix in malignancy

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Roles of matrix metalloproteinases in tumor metastasis and angiogenesis

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Expression of matrix metalloproteinase-10 in renal cell carcinoma and its prognostic role

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

An alternate perspective on the roles of TIMPs and MMPs in pathology

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Extrapineal melatonin: sources, regulation, and potential functions.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Melatonin: an ancient molecule that makes oxygen metabolically tolerable.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Mechanisms of cancer inhibition by melatonin

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Basic mechanisms involved in the anti-cancer effects of melatonin

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Molecular mechanisms of the pro-apoptotic actions of melatonin in cancer: a review

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

ROCK-regulated cytoskeletal dynamics participate in the inhibitory effect of melatonin on cancer cell migration

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Inhibition of matrix metalloproteinase-9 and nuclear factor kappa B contribute to melatonin prevention of motility and invasiveness in HepG2 liver cancer cells.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Melatonin suppresses migration and invasion via inhibition of oxidative stress pathway in glioma cells

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Overexpression of the MT1 melatonin receptor in MCF-7 human breast cancer cells inhibits mammary tumor formation in nude mice

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Melatonin and mammary pathological growth.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Strategies for MMP inhibition in cancer: innovations for the post-trial era.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Imbalance between MMP-2, 9 and TIMP-1 promote the invasion and metastasis of renal cell carcinoma via SKP2 signaling pathways

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Lycopene inhibits matrix metalloproteinase-9 expression and down-regulates the binding activity of nuclear factor-kappa B and stimulatory protein-1.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

In vitro effects of melatonin on cell proliferation in a colon adenocarcinoma line

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

The oncostatic action of melatonin in an ovarian carcinoma cell line

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

HDAC1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Randomized study with the pineal hormone melatonin versus supportive care alone in advanced nonsmall cell lung cancer resistant to a first-line chemotherapy containing cisplatin

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

The efficacy and safety of melatonin in concurrent chemotherapy or radiotherapy for solid tumors: a meta-analysis of randomized controlled trials

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Steps in tumor metastasis: new concepts from intravital videomicroscopy

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Matrix-metalloproteinases and their inhibitors in plasma and tumor tissue of patients with renal cell carcinoma.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Regulation of matrix metalloproteinase gene expression

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Melittin suppresses PMA-induced tumor cell invasion by inhibiting NF-kappaB and AP-1-dependent MMP-9 expression

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Carnosol inhibits the invasion of B16/F10 mouse melanoma cells by suppressing metalloproteinase-9 through down-regulating nuclear factor-kappa B and c-Jun

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Vascular cell adhesion molecule-1 expression in human intestinal microvascular endothelial cells is regulated by PI 3-kinase/Akt/MAPK/NF-kappaB: inhibitory role of curcumin

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Hyperexpression of mitogen-activated protein kinase in human breast cancer

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Melatonin inhibits matrix metalloproteinase-9 activity by binding to its active site

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1).

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Melatonin modulation of intracellular signaling pathways in hepatocarcinoma HepG2 cell line: role of the MT1 receptor.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12308

21 January 2018

Identifiers

10.1111/JPI.12308

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732239%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732239%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

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