(Q54248766)

26 May 2018

http://europepmc.org/abstract/MED/26333933

title

ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A. (English)

1 reference

26 May 2018

http://europepmc.org/abstract/MED/26333933

main subject

fibrodysplasia ossificans progressiva

0 references

author

Paul B Yu

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Andrew J Murphy

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Aris Economides

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Vincent Idone

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Sarah J Hatsell

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Dana M Alessi Wolken

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Lily Huang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Hyon J Kim

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Lili Wang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Xialing Wen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Kalyan C Nannuru

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Johanna Jimenez

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Liqin Xie

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Nanditha Das

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Genevieve Makhoul

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Rostislav Chernomorsky

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

David D'Ambrosio

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Richard A Corpina

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Christopher J Schoenherr

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Kieran Feeley

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

George D Yancopoulos

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

English

0 references

publication date

1 September 2015

1 reference

26 May 2018

http://europepmc.org/abstract/MED/26333933

published in

Science Translational Medicine

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

303

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

303ra137

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

1 June 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6164166/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Fibrodysplasia ossificans progressiva: clinical course, genetic mutations and genotype-phenotype correlation

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

In vitro analyses of the dysregulated R206H ALK2 kinase-FKBP12 interaction associated with heterotopic ossification in FOP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Structure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressiva

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Constitutively active ALK2 receptor mutants require type II receptor cooperation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Establishment of a novel model of chondrogenesis using murine embryonic stem cells carrying fibrodysplasia ossificans progressiva-associated mutant ALK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Mutant activin-like kinase 2 in fibrodysplasia ossificans progressiva are activated via T203 by BMP type II receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Fibrodysplasia ossificans progressiva-related activated activin-like kinase signaling enhances osteoclast formation during heterotopic ossification in muscle tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Alk2 regulates early chondrogenic fate in fibrodysplasia ossificans progressiva heterotopic endochondral ossification

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

An Acvr1 R206H knock-in mouse has fibrodysplasia ossificans progressiva

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Rapid generation of inducible mouse mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Proteomic identification and functional validation of activins and bone morphogenetic protein 11 as candidate novel muscle mass regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Characterization of the ligand binding functionality of the extracellular domain of activin receptor type IIb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Reconstitution and analysis of soluble inhibin and activin receptor complexes in a cell-free system

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Fibrodysplasia ossificans progressiva: clinical and genetic aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

When versatility matters: activins/inhibins as key regulators of immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

The regulation and functions of activin and follistatin in inflammation and immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Generation of a mouse with conditionally activated signaling through the BMP receptor, ALK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

BMP type I receptor inhibition reduces heterotopic [corrected] ossification

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Loss of BMPR2 leads to high bone mass due to increased osteoblast activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Single-dose, randomized, double-blind, placebo-controlled study of ACE-011 (ActRIIA-IgG1) in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Blockade of ActRIIB signaling triggers muscle fatigability and metabolic myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Conditionals by inversion provide a universal method for the generation of conditional alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

A new logic for DNA engineering using recombination in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

In vivo somatic cell gene transfer of an engineered Noggin mutein prevents BMP4-induced heterotopic ossification

21 January 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6164166

GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex

2 November 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6164166

A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse

2 November 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAC4358

Functional modeling of the ACVR1 (R206H) mutation in FOP

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26333933

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Creation and use of a cre recombinase transgenic database

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26333933

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCITRANSLMED.AAC4358

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26333933%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference