(Q54330869)

27 May 2018

title

The "HER2-PI3K/Akt-FASN Axis" regulated malignant phenotype of colorectal cancer cells. (English)

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27 May 2018

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Nan Li

1

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27 May 2018

Xiaodong Bu

2

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27 May 2018

Peng Wu

3

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27 May 2018

Pingping Wu

4

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27 May 2018

Peilin Huang

5

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27 May 2018

publication date

6 January 2012

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27 May 2018

published in

Lipids

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27 May 2018

volume

47

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27 May 2018

issue

4

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27 May 2018

page(s)

403-411

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27 May 2018

HER2 expression in breast cancer cells is downregulated upon active targeting by antibody-engineered multifunctional nanoparticles in mice

cites work

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12 December 2020

Signal transduction and oncogenesis by ErbB/HER receptors

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12 December 2020

Fatty acid synthase and cancer: new application of an old pathway

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12 December 2020

EGF-ERBB signalling: towards the systems level

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12 December 2020

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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12 December 2020

Expression of the tyrosine kinase activity growth factor receptors (EGFR, ERB B2, ERB B3) in colorectal adenocarcinomas and adenomas

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12 December 2020

Pharmacological inhibitor of fatty acid synthase suppresses growth and invasiveness of renal cancer cells

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12 December 2020

Pharmacological inhibition of fatty acid synthase (FAS): a novel therapeutic approach for breast cancer chemoprevention through its ability to suppress Her-2/neu (erbB-2) oncogene-induced malignant transformation.

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12 December 2020

Diosgenin, a naturally occurring steroid, suppresses fatty acid synthase expression in HER2-overexpressing breast cancer cells through modulating Akt, mTOR and JNK phosphorylation

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12 December 2020

Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer

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12 December 2020

Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology

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12 December 2020

Biologic and therapeutic role of HER2 in cancer

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12 December 2020

Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells

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12 December 2020

Untangling the ErbB signalling network

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12 December 2020

Fatty acid synthase inhibition with Orlistat promotes apoptosis and reduces cell growth and lymph node metastasis in a mouse melanoma model

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12 December 2020

Fatty acid synthase, a proficient multifunctional enzyme

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12 December 2020

Cancer statistics, 2008

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12 December 2020

Interaction between fatty acid synthase- and ErbB-systems in ovarian cancer cells

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12 December 2020

Inhibitor of fatty acid synthase induced apoptosis in human colonic cancer cells

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12 December 2020

Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells.

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12 December 2020

HER2-targeted therapies: how far we've come--and where we're headed.

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12 December 2020

Transcriptome analysis of HER2 reveals a molecular connection to fatty acid synthesis.

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12 December 2020

Targeting fatty acid synthase: potential for therapeutic intervention in her-2/neu-overexpressing breast cancer

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12 December 2020

The dual EGFR/HER2 inhibitor lapatinib synergistically enhances the antitumor activity of the histone deacetylase inhibitor panobinostat in colorectal cancer models.

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12 December 2020

Architecture of mammalian fatty acid synthase at 4.5 A resolution

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12 December 2020

EGCG inhibits protein synthesis, lipogenesis, and cell cycle progression through activation of AMPK in p53 positive and negative human hepatoma cells

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12 December 2020

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

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12 December 2020

A new mechanism of drug resistance in breast cancer cells: fatty acid synthase overexpression-mediated palmitate overproduction

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12 December 2020

10.1007/S11745-011-3649-7

Identifiers

DOI

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27 May 2018

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27 May 2018