(Q54331684)

27 May 2018

title

Unidirectional peristaltic movement in multisite drug binding pockets of AcrB from molecular dynamics simulations. (English)

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27 May 2018

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3

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27 May 2018

Tingjun Hou

series ordinal

2

object named as

Tingjun Hou

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27 May 2018

Zhiwei Feng

1

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27 May 2018

publication date

1 October 2012

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27 May 2018

published in

Molecular BioSystems

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27 May 2018

volume

8

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27 May 2018

issue

10

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27 May 2018

page(s)

2699-2709

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27 May 2018

Role of water during the extrusion of substrates by the efflux transporter AcrB.

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Functional rotation of the transporter AcrB: insights into drug extrusion from simulations

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Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB.

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Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism.

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Drug export pathway of multidrug exporter AcrB revealed by DARPin inhibitors

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Prediction of the 3D structure and dynamics of human DP G-protein coupled receptor bound to an agonist and an antagonist

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Covalently linked trimer of the AcrB multidrug efflux pump provides support for the functional rotating mechanism

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Three ways in, one way out: water dynamics in the trans-membrane domains of the inner membrane translocase AcrB

21 January 2018

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Studies on the Interactions between β2 Adrenergic Receptor and Gs Protein by Molecular Dynamics Simulations

21 January 2018

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21 January 2018

Identifiers

DOI

10.1039/C2MB25184A

1 reference

27 May 2018

1 reference

27 May 2018