(Q54332608)

27 May 2018

title

p85 protein expression is associated with poor survival in HER2-positive patients with advanced breast cancer treated with trastuzumab. (English)

1 reference

27 May 2018

author

Mattheos Bobos

2

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27 May 2018

George Fountzilas

16

George Fountzilas

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27 May 2018

Anastasia G Eleftheraki

5

Anastasia G Eleftheraki

1 reference

27 May 2018

Vassiliki Kotoula

4

Vassiliki Kotoula

1 reference

27 May 2018

Dimitrios Pectasides

11

Dimitrios Pectasides

1 reference

27 May 2018

Eleni Timotheadou

7

Eleni Timotheadou

1 reference

27 May 2018

Angelos Koutras

10

Angelos Koutras

1 reference

27 May 2018

Evangelia Razis

13

Evangelia Razis

1 reference

27 May 2018

George Pentheroudakis

8

George Pentheroudakis

1 reference

27 May 2018

Pavlos Papakostas

12

Pavlos Papakostas

1 reference

27 May 2018

Konstantine T Kalogeras

15

Konstantine T Kalogeras

1 reference

27 May 2018

Amanda Psyrri

9

Amanda Psyrri

1 reference

27 May 2018

Kitty Pavlakis

1

Kitty Pavlakis

1 reference

27 May 2018

Anna Batistatou

3

Anna Batistatou

1 reference

27 May 2018

author name string

Anastasios Stofas

6

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27 May 2018

Christos Christodoulou

14

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27 May 2018

publication date

8 August 2014

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27 May 2018

Pathology Oncology Research

published in

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27 May 2018

volume

21

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27 May 2018

issue

2

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27 May 2018

page(s)

273-282

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27 May 2018

Class IA phosphoinositide 3-kinases are obligate p85-p110 heterodimers

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E-cadherin directly contributes to PI3K/AKT activation by engaging the PI3K-p85 regulatory subunit to adherens junctions of ovarian carcinoma cells

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Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN+/- mice by the p85 regulatory subunits of phosphoinositide 3-kinase

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Topographical expression of class IA and class II phosphoinositide 3-kinase enzymes in normal human tissues is consistent with a role in differentiation

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PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

21 January 2018

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Human breast cancer cells selected for resistance to trastuzumab in vivo overexpress epidermal growth factor receptor and ErbB ligands and remain dependent on the ErbB receptor network

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Implications of the cancer stem-cell hypothesis for breast cancer prevention and therapy

21 January 2018

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Overexpression of phosphatidylinositol 3-kinase in human lung cancer

21 January 2018

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Phosphoinositide 3-kinase signalling pathways

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Identifiers

DOI

1 reference

27 May 2018

1 reference

27 May 2018