(Q54365461)

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Ebselen inhibits tumor necrosis factor-alpha-induced c-Jun N-terminal kinase activation and adhesion molecule expression in endothelial cells.

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Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/14720501

Ebselen inhibits tumor necrosis factor-alpha-induced c-Jun N-terminal kinase activation and adhesion molecule expression in endothelial cells. (English)

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/14720501

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Masanori Yoshizumi

1

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Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/14720501

Yoshiko Fujita

2

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Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/14720501

Yuki Izawa

3

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Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/14720501

Yuki Suzaki

4

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Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/14720501

Moe Kyaw

5

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Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/14720501

Nermin Ali

6

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Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/14720501

Koichiro Tsuchiya

7

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Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/14720501

Shoji Kagami

8

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Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/14720501

Seiji Yano

9

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Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/14720501

Saburo Sone

10

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Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/14720501

Toshiaki Tamaki

11

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28 May 2018

http://europepmc.org/abstract/MED/14720501

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1 January 2004

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28 May 2018

http://europepmc.org/abstract/MED/14720501

Experimental Cell Research

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28 May 2018

http://europepmc.org/abstract/MED/14720501

292

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28 May 2018

http://europepmc.org/abstract/MED/14720501

1

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28 May 2018

http://europepmc.org/abstract/MED/14720501

1-10

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28 May 2018

http://europepmc.org/abstract/MED/14720501

Atherosclerosis — An Inflammatory Disease

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Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

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Endothelial cell inflammatory responses to tumor necrosis factor alpha. Ceramide-dependent and -independent mitogen-activated protein kinase cascades

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Tumor necrosis factor/cachectin increases permeability of endothelial cell monolayers by a mechanism involving regulatory G proteins

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Mechanism of human lymphotoxin and tumor necrosis factor induced destruction of cells in vitro: phospholipase activation and deacylation of specific-membrane phospholipids

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Tumor necrosis factor-induced degranulation in adherent human neutrophils is dependent on CD11b/CD18-integrin-triggered oscillations of cytosolic free Ca2+

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The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling

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Fluid shear stress inhibits TNF-alpha activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: Inhibitory crosstalk among MAPK family members

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A novel biologically active seleno-organic compound—1

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A novel biologically active seleno-organic compound--II. Activity of PZ 51 in relation to glutathione peroxidase

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7 January 2021

Kinetic mechanism and substrate specificity of glutathione peroxidase activity of ebselen (PZ51).

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7 January 2021

A novel biologically active seleno-organic compound--V. Inhibition by ebselen (PZ 51) of rat peritoneal neutrophil lipoxygenase

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7 January 2021

Neuroprotective efficacy of ebselen, an anti-oxidant with anti-inflammatory actions, in a rodent model of permanent middle cerebral artery occlusion

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7 January 2021

Ebselen attenuates oxidative stress-induced apoptosis via the inhibition of the c-Jun N-terminal kinase and activator protein-1 signalling pathway in PC12 cells

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7 January 2021

The neuroprotective efficacy of ebselen (a glutathione peroxidase mimic) on brain damage induced by transient focal cerebral ischaemia in the rat

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7 January 2021

Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group

1 reference

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7 January 2021

Reactive oxygen species mediate cytokine activation of c-Jun NH2-terminal kinases

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Src and Cas mediate JNK activation but not ERK1/2 and p38 kinases by reactive oxygen species

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7 January 2021

Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression

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7 January 2021

From receptors to stress-activated MAP kinases

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Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin.

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7 January 2021

Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

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7 January 2021

A role for c-Raf kinase and Ha-Ras in cytokine-mediated induction of cell adhesion molecules.

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7 January 2021

The role of p38 map kinase in tumor necrosis factor-induced redistribution of vascular endothelial cadherin and increased endothelial permeability

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7 January 2021

Selenoorganic compound, ebselen, inhibits nitric oxide and tumor necrosis factor-alpha production by the modulation of jun-N-terminal kinase and the NF-kappab signaling pathway in rat Kupffer cells

1 reference

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7 January 2021

Inhibition of superoxide anion production in guinea pig polymorphonuclear leukocytes by a seleno-organic compound, ebselen.

1 reference

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Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species

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7 January 2021

c-Jun triggers apoptosis in human vascular endothelial cells

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Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death

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TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival

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TRAF6 is a signal transducer for interleukin-1

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Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

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Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

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ASK1 is essential for JNK/SAPK activation by TRAF2

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Selenite suppresses hydrogen peroxide-induced cell apoptosis through inhibition of ASK1/JNK and activation of PI3-K/Akt pathways

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Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

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Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner

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Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant

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Redox factor-1/APE suppresses oxidative stress by inhibiting the rac1 GTPase

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Oxidant signaling in vascular cell growth, death, and survival : a review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling.

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Role of isoprenylcysteine carboxyl methyltransferase in tumor necrosis factor-alpha stimulation of expression of vascular cell adhesion molecule-1 in endothelial cells

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Tumor necrosis factor alpha-induced E-selectin expression is activated by the nuclear factor-kappaB and c-JUN N-terminal kinase/p38 mitogen-activated protein kinase pathways

1 reference

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7 January 2021

Identifiers

10.1016/J.YEXCR.2003.08.003

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/14720501

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/14720501

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