(Q54440606)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23542006%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

A homology model of HIV-1 integrase and analysis of mutations designed to test the model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23542006%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

4

Yves Pommier

1 reference

PubMed publication ID

29 May 2018

5

Stephen H Hughes

1 reference

PubMed publication ID

29 May 2018

Barry C Johnson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23542006%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Mathieu Métifiot

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23542006%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Andrea Ferris

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23542006%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Yves Pommier

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23542006%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Stephen H Hughes

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23542006%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

language of work or name

English

0 references

publication date

27 March 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23542006%20AND%20SRC:MED&resulttype=core&format=json

Journal of Molecular Biology

27 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23542006%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

volume

425

1 reference

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27 February 2020

issue

12

1 reference

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27 February 2020

page(s)

2133-2146

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23542006%20AND%20SRC:MED&resulttype=core&format=json

Structural basis for HIV-1 DNA integration in the human genome, role of the LEDGF/P75 cofactor

27 February 2020

cites work

1 reference

12 December 2020

Molecular dynamics approaches estimate the binding energy of HIV-1 integrase inhibitors and correlate with in vitro activity

1 reference

12 December 2020

Molecular mechanisms by which human immunodeficiency virus type 1 integrase stimulates the early steps of reverse transcription

1 reference

12 December 2020

Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases

1 reference

12 December 2020

Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium

1 reference

12 December 2020

Structure-based modeling of the functional HIV-1 intasome and its inhibition

1 reference

12 December 2020

Identification of amino acids in HIV-1 and avian sarcoma virus integrase subsites required for specific recognition of the long terminal repeat Ends

1 reference

12 December 2020

DNA bending creates favored sites for retroviral integration: an explanation for preferred insertion sites in nucleosomes.

1 reference

12 December 2020

Characterization of the minimal DNA-binding domain of the HIV integrase protein

1 reference

12 December 2020

Biochemical and pharmacological analyses of HIV-1 integrase flexible loop mutants resistant to raltegravir

1 reference

12 December 2020

SH3-like fold proteins are structurally conserved and functionally divergent

1 reference

12 December 2020

2,3-dihydro-6,7-dihydroxy-1H-isoindol-1-one-based HIV-1 integrase inhibitors

1 reference

12 December 2020

The mechanism of retroviral integration from X-ray structures of its key intermediates

1 reference

12 December 2020

Specificity of LTR DNA recognition by a peptide mimicking the HIV-1 integrase {alpha}4 helix

1 reference

12 December 2020

The influence of DNA and nucleosome structure on integration events directed by HIV integrase

1 reference

12 December 2020

Resistance to raltegravir highlights integrase mutations at codon 148 in conferring cross-resistance to a second-generation HIV-1 integrase inhibitor

1 reference

12 December 2020

Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity

1 reference

12 December 2020

Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance.

1 reference

12 December 2020

Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA binding

1 reference

12 December 2020

Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75.

1 reference

12 December 2020

Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein

1 reference

12 December 2020

Replication of phenotypically mixed human immunodeficiency virus type 1 virions containing catalytically active and catalytically inactive reverse transcriptase

1 reference

12 December 2020

Solution structure of the DNA binding domain of HIV-1 integrase

1 reference

12 December 2020

HIV-1 integrase crosslinked oligomers are active in vitro

1 reference

12 December 2020

Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase.

1 reference

12 December 2020

A large nucleoprotein assembly at the ends of the viral DNA mediates retroviral DNA integration

1 reference

12 December 2020

A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication

1 reference

12 December 2020

X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform

1 reference

12 December 2020

Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase

1 reference

12 December 2020

In vivo analysis of retroviral integrase structure and function

1 reference

12 December 2020

Retroviral intasome assembly and inhibition of DNA strand transfer

1 reference

12 December 2020

Sequential deletion of the integrase (Gag-Pol) carboxyl terminus reveals distinct phenotypic classes of defective HIV-1.

1 reference

12 December 2020

Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding

1 reference

12 December 2020

Genetic analyses of conserved residues in the carboxyl-terminal domain of human immunodeficiency virus type 1 integrase

1 reference

12 December 2020

Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication

1 reference

12 December 2020

Localization of DNA binding activity of HIV-1 integrase to the C-terminal half of the protein

1 reference

12 December 2020

Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction

1 reference

12 December 2020

Solution structure of the N-terminal zinc binding domain of HIV-1 integrase

1 reference

12 December 2020

Structural and Functional Analyses of the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir (S/GSK1349572)

1 reference

12 December 2020

Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA

1 reference

12 December 2020

Retroviral DNA integration directed by HIV integration protein in vitro

1 reference

12 December 2020

Refined solution structure of the C-terminal DNA-binding domain of human immunovirus-1 integrase

1 reference

12 December 2020

Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNa termini mediated by the viral integrase protein

1 reference

12 December 2020

Relationship between the oligomeric status of HIV-1 integrase on DNA and enzymatic activity

1 reference

12 December 2020

Modeling the late steps in HIV-1 retroviral integrase-catalyzed DNA integration

1 reference

12 December 2020

Asymmetric processing of human immunodeficiency virus type 1 cDNA in vivo: implications for functional end coupling during the chemical steps of DNA transposition

1 reference

12 December 2020

Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity

1 reference

12 December 2020

Mapping features of HIV-1 integrase near selected sites on viral and target DNA molecules in an active enzyme-DNA complex by photo-cross-linking.

1 reference

12 December 2020

Derivation of an amino acid similarity matrix for peptide: MHC binding and its application as a Bayesian prior

1 reference

12 December 2020

Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus

1 reference

12 December 2020

Integration requires a specific interaction of the donor DNA terminal 5'-cytosine with glutamine 148 of the HIV-1 integrase flexible loop

1 reference

12 December 2020

10.1016/J.JMB.2013.03.027

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23542006%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23542006%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

PubMed publication ID

23542006

1 reference