(Q45888150)

17 December 2017

title

Integration requires a specific interaction of the donor DNA terminal 5'-cytosine with glutamine 148 of the HIV-1 integrase flexible loop (English)

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17 December 2017

Webster Santos

2

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Yves Pommier

8

object named as

Yves Pommier

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17 December 2017

Allison A Johnson

1

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17 December 2017

Godwin C G Pais

3

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17 December 2017

Christophe Marchand

4

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17 December 2017

Ronak Amin

5

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17 December 2017

Terrence R Burke

6

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17 December 2017

Gregory Verdine

7

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17 December 2017

language of work or name

English

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publication date

27 October 2005

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17 December 2017

Journal of Biological Chemistry

published in

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17 December 2017

volume

281

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17 December 2017

issue

1

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17 December 2017

page(s)

461-467

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17 December 2017

cites work

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The mobility of an HIV-1 integrase active site loop is correlated with catalytic activity

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Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

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Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium

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Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein

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The catalytic domain of human immunodeficiency virus integrase: ordered active site in the F185H mutant

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Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding

21 January 2018

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Structure and function of HIV-1 integrase

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Integration of human immunodeficiency virus DNA: adduct interference analysis of required DNA sites

21 January 2018

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A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro

21 January 2018

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Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction

21 January 2018

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Modifying the helical structure of DNA by design: recruitment of an architecture-specific protein to an enforced DNA bend.

21 January 2018

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Determinants of Mg2+-dependent activities of recombinant human immunodeficiency virus type 1 integrase

21 January 2018

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Chemical trapping of ternary complexes of human immunodeficiency virus type 1 integrase, divalent metal, and DNA substrates containing an abasic site. Implications for the role of lysine 136 in DNA binding

21 January 2018

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Genetic analyses of DNA-binding mutants in the catalytic core domain of human immunodeficiency virus type 1 integrase

21 January 2018

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Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases

21 January 2018

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Covalent trapping of protein-DNA complexes

21 January 2018

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Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes

21 January 2018

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Identification of amino acids in HIV-2 integrase involved in site-specific hydrolysis and alcoholysis of viral DNA termini

21 January 2018

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Metal binding by the D,DX35E motif of human immunodeficiency virus type 1 integrase: selective rescue of Cys substitutions by Mn2+ in vitro

21 January 2018

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Divalent cations stimulate preferential recognition of a viral DNA end by HIV-1 integrase

21 January 2018

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Pre-organized structure of viral DNA at the binding-processing site of HIV-1 integrase

21 January 2018

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Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques

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Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

21 January 2018

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HIV-1 integrase inhibitors: a decade of research and two drugs in clinical trial

21 January 2018

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Structure of human dCK suggests strategies to improve anticancer and antiviral therapy

21 January 2018

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Diketo acid inhibitor mechanism and HIV-1 integrase: implications for metal binding in the active site of phosphotransferase enzymes

21 January 2018

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Metal-dependent inhibition of HIV-1 integrase by beta-diketo acids and resistance of the soluble double-mutant (F185K/C280S).

21 January 2018

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Position-specific suppression and enhancement of HIV-1 integrase reactions by minor groove benzo[a]pyrene diol epoxide deoxyguanine adducts: implications for molecular interactions between integrase and substrates

21 January 2018

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MODIFIED OLIGONUCLEOTIDES: Synthesis and Strategy for Users

21 January 2018

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Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design

21 January 2018

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Structure activity of 3-aryl-1,3-diketo-containing compounds as HIV-1 integrase inhibitors.

21 January 2018

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Active site binding modes of HIV-1 integrase inhibitors

21 January 2018

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Structural determinants for HIV-1 integrase inhibition by beta-diketo acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511348200

21 January 2018

Identifiers

DOI

10.1074/JBC.M511348200

1 reference

17 December 2017

1 reference

17 December 2017