(Q5446672)

PubChem

PubChem CID

10034073

Dificid (English)

19 November 2016

CCc1c(Cl)c(O)c(Cl)c(O)c1C(=O)O[C@H]1[C@H](O)[C@H](OC)[C@H](OC/C2=C\C=C\C[C@H](O)/C(C)=C/[C@H](CC)[C@@H](O[C@@H]3OC(C)(C)[C@@H](OC(=O)C(C)C)[C@H](O)[C@@H]3O)/C(C)=C/C(C)=C/C[C@@H]([C@@H](C)O)OC2=O)O[C@@H]1C

0 references

defined daily dose

0.4 gram

route of administration

oral administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=A07AA12

active ingredient in

Dificlir

1 reference

European Medicines Agency product number

EMEA/H/C/002087

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/002087/human_med_001511.jsp

22 March 2017

1 reference

14 February 2018

World Health Organisation international non-proprietary name

Fidaxomicin (English)

1 reference

Fidaxomicin (English)

medical condition treated

19 January 2016

Clostridioides difficile colitis

1 reference

Drug Indications Extracted from FAERS

Clostridium difficile intestinal infectious disease

2 October 2018

start time

27 May 2011

approved by

Food and Drug Administration

2 references

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/Z5N076G8YQ

http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/201699s000lbl.pdf

https://www.nature.com/articles/s41586-022-04545-z

pregnancy category

Australian pregnancy category B1

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category B

1 reference

imported from Wikimedia project

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category E

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Fidaxomicin

last update

8 August 2017

subject has role

DNA polymerase inhibitors

1 reference

5 March 2018

1 reference

‎WHO Aware Classification

watch

1 reference

2023 ‎AWaRe classification‎

Identifiers

InChI

InChI=1S/C52H74Cl2O18/c1-13-30-22-26(6)33(56)18-16-15-17-31(23-66-51-45(65-12)42(61)44(29(9)67-51)69-49(64)35-32(14-2)36(53)39(58)37(54)38(35)57)48(63)68-34(28(8)55)20-19-25(5)21-27(7)43(30)70-50-41(60)40(59)46(52(10,11)72-50)71-47(62)24(3)4/h15-17,19,21-22,24,28-30,33-34,40-46,50-51,55-61H,13-14,18,20,23H2,1-12H3/b16-15+,25-19+,26-22+,27-21+,31-17+/t28-,29-,30+,33+,34?,40-,41+,42+,43+,44-,45+,46+,50-,51-/m1/s1

0 references

InChI=1S/C52H74Cl2O18/c1-13-30-22-26(6)33(56)18-16-15-17-31(23-66-51-45(65-12)42(61)44(29(9)67-51)69-49(64)35-32(14-2)36(53)39(58)37(54)38(35)57)48(63)68-34(28(8)55)20-19-25(5)21-27(7)43(30)70-50-41(60)40(59)46(52(10,11)72-50)71-47(62)24(3)4/h15-17,19,21-22,24,28-30,33-34,40-46,50-51,55-61H,13-14,18,20,23H2,1-12H3/b16-15+,25-19+,26-22+,27-21+,31-17+/t28-,29-,30+,33+,34+,40-,41+,42+,43+,44-,45+,46+,50-,51-/m1/s1

0 references

InChIKey

ZVGNESXIJDCBKN-UUEYKCAUSA-N

1 reference

Dificid (English)

ZVGNESXIJDCBKN-KFGPIHIUSA-N

19 November 2016

2 references

ChEBI release 2020-09-01

Total Synthesis of the Glycosylated Macrolide Antibiotic Fidaxomicin

CAS Registry Number

873857-62-6

2 references

Global Substance Registration System

UNII

Z5N076G8YQ

fidaxomicin (English)

19 November 2016

CAS (formerly Chemical Abstracts Service)

25 January 2022

1 reference

Fidaxomicin (English)

19 November 2016

1 reference

Dificid (English)

19 November 2016

mapping relation type

2 references

Fidaxomicin (English)

19 January 2016

ChEBI release 2021-03-01

1 reference

FIDAXOMICIN (English)

19 November 2016

1 reference

0 references

692-555-6

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.220.590

27 December 2018

ECHA Substance Infocard ID

3-(((6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl)oxy)-methyl)-12(R)-[(6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl)oxy]-11(S)-ethyl-8(S)-hydroxy-18(S)-(1(R)-hydroxyethyl)-9,13,15-trimethyloxacyclooctadeca-3,5,9,13,15-pentaene-2-one (English)

quotation

CAS no.: 873857-62-6 (English)

100.220.590

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.220.590

27 December 2018

3-(((6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl)oxy)-methyl)-12(R)-[(6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl)oxy]-11(S)-ethyl-8(S)-hydroxy-18(S)-(1(R)-hydroxyethyl)-9,13,15-trimethyloxacyclooctadeca-3,5,9,13,15-pentaene-2-one (English)

quotation

CAS no.: 873857-62-6 (English)

1 reference