(Q54506056)

30 May 2018

title

TCR-induced T cell activation leads to simultaneous phosphorylation at Y505 and Y394 of p56(lck) residues. (English)

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30 May 2018

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3

Anjali Joshi

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30 May 2018

author name string

Alice M Nyakeriga

series ordinal

1

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30 May 2018

Himanshu Garg

series ordinal

2

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30 May 2018

publication date

6 June 2012

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30 May 2018

published in

Cytometry Part A

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30 May 2018

volume

81

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30 May 2018

issue

9

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30 May 2018

page(s)

797-805

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30 May 2018

Profound block in thymocyte development in mice lacking p56lck

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Molecular interactions, T-cell subsets and a role of the CD4/CD8:p56lck complex in human T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Peptide and protein phosphorylation by protein tyrosine kinase Csk: insights into specificity and mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Structural differences between repressed and derepressed forms of p60c-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

The regulation of antigen-receptor signaling by protein tyrosine phosphatases: a hole in the story

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Positive and negative regulation of Src-family membrane kinases by CD45.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Involvement of CD4 D3-D4 membrane proximal extracellular domain for the inhibitory effect of oxidative stress on activation-induced CD4 down-regulation and its possible role for T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

The effect of CD4 receptor downregulation and its downstream signaling molecules on HIV-1 latency

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

HIV-1 Nef plays an essential role in two independent processes in CD4 down-regulation: dissociation of the CD4-p56(lck) complex and targeting of CD4 to lysosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Engagement of the CD4 receptor affects the redistribution of Lck to the immunological synapse in primary T cells: implications for T-cell activation during human immunodeficiency virus type 1 infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Identification of protein kinases dysregulated in CD4(+) T cells in pathogenic versus apathogenic simian immunodeficiency virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Atorvastatin restores Lck expression and lipid raft-associated signaling in T cells from patients with systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Disruption of HLA-DR raft, deregulations of Lck-ZAP-70-Cbl-b cross-talk and miR181a towards T cell hyporesponsiveness in leprosy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Measurement of MAP kinase activation by flow cytometry using phospho-specific antibodies to MEK and ERK: potential for pharmacodynamic monitoring of signal transduction inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Immunoreactivity of Stat5 phosphorylated on tyrosine as a cell-based measure of Bcr/Abl kinase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Cytokine receptor signalling in neonatal macrophages: defective STAT-1 phosphorylation in response to stimulation with IFN-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

A rapid flow cytometric method for the detection of intracellular cyclooxygenases in human whole blood monocytes and a COX-2 inducible human cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Fluorescence-intensity multiplexing: simultaneous seven-marker, two-color immunophenotyping using flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Constitutively active Lck kinase in T cells drives antigen receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

The activated form of the Lck tyrosine protein kinase in cells exposed to hydrogen peroxide is phosphorylated at both Tyr-394 and Tyr-505

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Genetically encoded Förster resonance energy transfer sensors for the conformation of the Src family kinase Lck.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Cytometry of intracellular signaling: from laboratory bench to clinical application

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Phospho flow cytometry methods for the analysis of kinase signaling in cell lines and primary human blood samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Multiparameter analysis of intracellular phosphoepitopes in immunophenotyped cell populations by flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Single-cell phospho-protein analysis by flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Modulated multiparametric phosphoflow cytometry in hematological malignancies: technology and clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Duration of antigen receptor signaling determines T-cell tolerance or activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Development and application of 'phosphoflow' as a tool for immunomonitoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Potential positive and negative autoregulation of p60c-src by intermolecular autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Activation of the Lck tyrosine protein kinase by hydrogen peroxide requires the phosphorylation of Tyr-394.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation site

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Regulation of Lck activity by CD4 and CD28 in the immunological synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

Reconstitution of T cell antigen receptor-induced Erk2 kinase activation in Lck-negative JCaM1 cells by Syk

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

7 January 2021

The role of p56lck in CD4-mediated suppression of CD3-induced early signaling events in T lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

7 January 2021

The tyrosine kinase p56lck is essential in coxsackievirus B3-mediated heart disease

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

7 January 2021

Detection of intracellular phosphorylated STAT-1 by flow cytometry

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

7 January 2021

Simultaneous detection of ERK-, p38-, and JNK-MAPK phosphorylation in human adipose-derived stem cells using the Cytometric Bead Array technology

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

7 January 2021

Measurement of intracellular calcium ions by flow cytometry

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

7 January 2021

Correlation of the phosphorylation states of pp60c-src with tyrosine kinase activity: the intramolecular pY530-SH2 complex retains significant activity if Y419 is phosphorylated

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.22070

7 January 2021

Identifiers

DOI

10.1002/CYTO.A.22070

1 reference

30 May 2018

PubMed ID

22674786

1 reference

30 May 2018