(Q54521300)

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Stimulated erythropoiesis with secondary iron loading leads to a decrease in hepcidin despite an increase in bone morphogenetic protein 6 expression.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449175%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Stimulated erythropoiesis with secondary iron loading leads to a decrease in hepcidin despite an increase in bone morphogenetic protein 6 expression (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449175%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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David M. Frazer

1

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27 January 2020

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27 January 2020

Gregory J Anderson

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27 January 2020

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Sarah J Wilkins

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27 January 2020

Alison C Badrick

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27 January 2020

Gordon D McLaren

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27 January 2020

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26 March 2012

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27 January 2020

British Journal of Haematology

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27 January 2020

157

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27 January 2020

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27 January 2020

615-626

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27 January 2020

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Characterization of the rat, mouse, and human genes of growth/differentiation factor-15/macrophage inhibiting cytokine-1 (GDF-15/MIC-1).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Severe iron deficiency blunts the response of the iron regulatory gene Hamp and pro-inflammatory cytokines to lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Reduced expression of ferroportin-1 mediates hyporesponsiveness of suckling rats to stimuli that reduce iron absorption.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

The orchestration of body iron intake: how and where do enterocytes receive their cues?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Delayed hepcidin response explains the lag period in iron absorption following a stimulus to increase erythropoiesis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Hepcidin and iron regulation, 10 years later

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following liver injury

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Contribution of STAT3 and SMAD4 pathways to the regulation of hepcidin by opposing stimuli.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Diferric transferrin regulates transferrin receptor 2 protein stability

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Iron-sensing proteins that regulate hepcidin and enteric iron absorption

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

The function of heme-regulated eIF2alpha kinase in murine iron homeostasis and macrophage maturation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

beta-Thalassemia: HiJAKing Ineffective Erythropoiesis and Iron Overload

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Regulation of TMPRSS6 by BMP6 and iron in human cells and mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Hepcidin in beta-thalassemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Liver iron concentrations and urinary hepcidin in beta-thalassemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Suppression of hepcidin during anemia requires erythropoietic activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Regulation of transferrin receptor 2 protein levels by transferrin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Nramp1 promotes efficient macrophage recycling of iron following erythrophagocytosis in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Iron Loading and Overloading due to Ineffective Erythropoiesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

A mouse model for beta 0-thalassemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

The effect of the iron saturation of transferrin on its binding and uptake by rabbit reticulocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09104.X

21 January 2018

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