(Q54524216)

30 May 2018

title

Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage-mediated chronic inflammation. (English)

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30 May 2018

Karin Scharffetter-Kochanek

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15

object named as

Karin Scharffetter-Kochanek

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30 May 2018

17

Pavel Strnad

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30 May 2018

author name string

Yoshiaki Sunami

1

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30 May 2018

Frank Leithäuser

2

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30 May 2018

Sarah Gul

3

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30 May 2018

Katja Fiedler

4

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30 May 2018

Nurdan Güldiken

5

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30 May 2018

Sigrid Espenlaub

6

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30 May 2018

Karl-Heinz Holzmann

7

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30 May 2018

Nora Hipp

8

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30 May 2018

Anca Sindrilaru

9

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30 May 2018

Tom Luedde

10

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30 May 2018

Bernd Baumann

11

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30 May 2018

Sebastian Wissel

12

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30 May 2018

Florian Kreppel

13

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30 May 2018

Marion Schneider

14

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30 May 2018

Stefan Kochanek

16

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30 May 2018

Thomas Wirth

18

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30 May 2018

language of work or name

English

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publication date

10 July 2012

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30 May 2018

published in

Hepatology

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30 May 2018

volume

56

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30 May 2018

issue

3

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30 May 2018

page(s)

1117-1128

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30 May 2018

1 reference

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Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species

1 reference

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Fibrogenic effect of oxidative stress on rat hepatic stellate cells

1 reference

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Hepatitis C virus-replicating hepatocytes induce fibrogenic activation of hepatic stellate cells.

1 reference

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Hepatic recruitment of the inflammatory Gr1+monocyte subset upon liver injury promotes hepatic fibrosis

1 reference

7 January 2021

Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis

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7 January 2021

A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways

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7 January 2021

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

1 reference

7 January 2021

NF-kappaB signaling, liver disease and hepatoprotective agents

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7 January 2021

NF-κB in the liver--linking injury, fibrosis and hepatocellular carcinoma

1 reference

7 January 2021

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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7 January 2021

IkappaB kinase complexes: gateways to NF-kappaB activation and transcription

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7 January 2021

NF-kappaB regulation in the immune system

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7 January 2021

High susceptibility to bacterial infection, but no liver dysfunction, in mice compromised for hepatocyte NF-kappaB activation

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7 January 2021

Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury

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7 January 2021

Genetic inactivation of RelA/p65 sensitizes adult mouse hepatocytes to TNF-induced apoptosis in vivo and in vitro.

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7 January 2021

IKK mediates ischemia-induced neuronal death

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7 January 2021

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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7 January 2021

Lymphotoxin and lipopolysaccharide induce NF-kappaB-p52 generation by a co-translational mechanism

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7 January 2021

Critical role of RelB serine 368 for dimerization and p100 stabilization

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7 January 2021

Keratin mutation predisposes to mouse liver fibrosis and unmasks differential effects of the carbon tetrachloride and thioacetamide models.

1 reference

7 January 2021

Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

1 reference

7 January 2021

TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer.

1 reference

7 January 2021

Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses.

1 reference

7 January 2021

Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis

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7 January 2021

Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice

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7 January 2021

Cellular immune reaction in the pancreas is induced by constitutively active IkappaB kinase-2.

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7 January 2021

Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo

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7 January 2021

Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma

1 reference

7 January 2021

Suppression of macrophage infiltration inhibits activation of hepatic stellate cells and liver fibrogenesis in rats

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7 January 2021

Dual role of CCR2 in the constitution and the resolution of liver fibrosis in mice

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7 January 2021

CCR2 promotes hepatic fibrosis in mice

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7 January 2021

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

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7 January 2021

Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver

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7 January 2021

Monocytes and macrophages as cellular targets in liver fibrosis

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7 January 2021

Identifiers

DOI

10.1002/HEP.25711

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30 May 2018

PubMed ID

22407857

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30 May 2018