(Q54558904)

31 May 2018

title

Transgenic mice expressing Tel-FLT3, a constitutively activated form of FLT3, develop myeloproliferative disease. (English)

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31 May 2018

author name string

Baldwin BR

1

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31 May 2018

Li L

2

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31 May 2018

Tse KF

3

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31 May 2018

Small S

4

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31 May 2018

Collector M

5

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31 May 2018

Whartenby KA

6

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31 May 2018

Sharkis SJ

7

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31 May 2018

Racke F

8

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31 May 2018

Huso D

9

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31 May 2018

Small D

10

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31 May 2018

publication date

1 February 2007

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31 May 2018

published in

Leukemia

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31 May 2018

volume

21

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31 May 2018

issue

4

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31 May 2018

page(s)

764-771

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31 May 2018

https://scigraph.springernature.com/pub.10.1038/sj.leu.2404532

exact match

0 references

cites work

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Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs

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Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

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Update in childhood acute myeloid leukemia: recent developments in the molecular basis of disease and novel therapies

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Normal and oncogenic FLT3

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FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model

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7 January 2021

FLT3-ITD and tyrosine kinase domain mutants induce 2 distinct phenotypes in a murine bone marrow transplantation model

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7 January 2021

FLT3 internal tandem duplication mutations induce myeloproliferative or lymphoid disease in a transgenic mouse model.

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7 January 2021

PML/RARalpha and FLT3-ITD induce an APL-like disease in a mouse model

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The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice

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STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells

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Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells

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A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations

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Constitutive activation of FLT3 stimulates multiple intracellular signal transducers and results in transformation.

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7 January 2021

Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

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7 January 2021

FLT3 is fused to ETV6 in a myeloproliferative disorder with hypereosinophilia and a t(12;13)(p13;q12) translocation.

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Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease

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Internal tandem duplications of the FLT3 gene are present in leukemia stem cells

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Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors

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Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector

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Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified

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FLT3 ligand induces the generation of functionally active dendritic cells in mice

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7 January 2021

Flt3 ligand and granulocyte-macrophage colony-stimulating factor preferentially expand and stimulate different dendritic and T-cell subsets.

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7 January 2021

Flt3 ligand lessens the growth of tumors obtained after colon cancer cell injection in rats but does not restore tumor-suppressed dendritic cell function

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7 January 2021

Flt3 ligand enhances the immunogenicity of a gag-based HIV-1 vaccine

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Reduced herpes simplex virus type 1 latency in Flt-3 ligand-treated mice is associated with enhanced numbers of natural killer and dendritic cells

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Identifiers

DOI

10.1038/SJ.LEU.2404532

1 reference

31 May 2018

Dimensions Publication ID

1051961395

0 references

Fatcat ID

release_osqrhm765zewpmlmffhobvy7cu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/osqrhm765zewpmlmffhobvy7cu

24 November 2022

mapped directly with Wikidata item

1 reference

31 May 2018