(Q34133267)

31 July 2017

title

Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease (English)

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31 July 2017

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2

Peter A Calabresi

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31 July 2017

8

Drew M Pardoll

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31 July 2017

5

David Kardian

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31 July 2017

3

Erin McCadden

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31 July 2017

Katharine A Whartenby

1

object named as

Katharine A Whartenby

1 reference

31 July 2017

Bao Nguyen

4

1 reference

31 July 2017

Tianhong Wang

6

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31 July 2017

Claudio Mosse

7

1 reference

31 July 2017

Donald Small

9

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31 July 2017

language of work or name

English

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publication date

4 November 2005

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Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

published in

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31 July 2017

volume

102

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31 July 2017

issue

46

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31 July 2017

page(s)

16741-16746

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Internal tandem duplication mutation of FLT3 blocks myeloid differentiation through suppression of C/EBPα expression

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

The roles of FLT3 in hematopoiesis and leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

A FLT3-targeted tyrosine kinase inhibitor is cytotoxic to leukemia cells in vitro and in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

Dendritic cells in models of tumor immunity. Role of Flt3 ligand

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

Flt3 ligand induces tyrosine phosphorylation of gab1 and gab2 and their association with shp-2, grb2, and PI3 kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

SHC and SHIP phosphorylation and interaction in response to activation of the FLT3 receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

Flt3 signaling involves tyrosyl-phosphorylation of SHP-2 and SHIP and their association with Grb2 and Shc in Baf3/Flt3 cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

FLT3 signaling in hematopoietic cells involves CBL, SHC and an unknown P115 as prominent tyrosine-phosphorylated substrates

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

c-kit ligand and Flt3 ligand: stem/progenitor cell factors with overlapping yet distinct activities

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

Induction of dendritic cells (DC) by Flt3 Ligand (FL) promotes the generation of tumor-specific immune responses in vivo.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

Murine flt3 ligand protects M1 leukemic cells from LIF-induced differentiation and suppression of self-renewal

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

Mitogenic signalling and substrate specificity of the Flk2/Flt3 receptor tyrosine kinase in fibroblasts and interleukin 3-dependent hematopoietic cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

Multiple sclerosis: oligodendrocytes in active lesions do not express class II major histocompatibility complex molecules.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

Flt3 ligand-generated murine plasmacytoid and conventional dendritic cells differ in their capacity to prime naive CD8 T cells and to generate memory cells in vivo.

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506088102

Constitutive activation of FLT3 stimulates multiple intracellular signal transducers and results in transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506088102

Novel FLT3 tyrosine kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506088102

Transfer of central nervous system autoantigens and presentation in secondary lymphoid organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506088102

Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506088102

CD4 and CD8 expression by human and mouse thymic dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506088102

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506088102

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506088102

Biologic effects and potential clinical applications of Flt3 ligand

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

Analysis of the mitogenic pathway of the FLT3 receptor and characterization in its C terminal region of a specific binding site for the PI3' kinase.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1283812

Cholesterol-lowering statins possess anti-inflammatory activity that might be useful for treatment of MS

28 October 2018

1 reference

12 December 2020

CD4+ T Cells Pass Through an Effector Phase During the Process of In Vivo Tolerance Induction

1 reference

12 December 2020

Pilot study of Flt3 ligand comparing intraperitoneal with subcutaneous routes on hematologic and immunologic responses in patients with peritoneal carcinomatosis and mesotheliomas

1 reference

12 December 2020

Flt3 ligand induces tumor regression and antitumor immune responses in vivo

1 reference

12 December 2020

Dendritic cell subtypes in mouse lymphoid organs: cross-correlation of surface markers, changes with incubation, and differences among thymus, spleen, and lymph nodes

1 reference

12 December 2020

FLT3-ligand administration inhibits liver metastases: role of NK cells

1 reference

12 December 2020

Synergistic action of fms-like tyrosine kinase 3 ligand and CD40 ligand in the induction of dendritic cells and generation of antitumor immunity in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0506088102

1 reference

release_zcx3rk7c3rhpldoak6w7kebyja

31 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zcx3rk7c3rhpldoak6w7kebyja

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1283812

1 reference

31 July 2017

1 reference