(Q54570256)

1 June 2018

title

Deregulation of FGFR1 and CDK6 oncogenic pathways in acute lymphoblastic leukaemia harbouring epigenetic modifications of the MIR9 family. (English)

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1 June 2018

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10

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author name string

Paula Rodriguez-Otero

1

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1 June 2018

José Román-Gómez

2

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1 June 2018

Amaia Vilas-Zornoza

3

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1 June 2018

Edurne San José-Eneriz

4

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1 June 2018

Vanesa Martín-Palanco

5

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1 June 2018

José Rifón

6

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1 June 2018

Antonio Torres

7

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1 June 2018

María José Calasanz

8

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1 June 2018

Xabier Agirre

9

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1 June 2018

language of work or name

English

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publication date

2 August 2011

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1 June 2018

British Journal of Haematology

published in

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1 June 2018

volume

155

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1 June 2018

issue

1

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1 June 2018

page(s)

73-83

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1 June 2018

Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition

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ASPP1, a common activator of TP53, is inactivated by aberrant methylation of its promoter in acute lymphoblastic leukemia.

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Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia

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The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function.

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Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression

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Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer

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Targeting FGFR3 in multiple myeloma: inhibition of t(4;14)-positive cells by SU5402 and PD173074.

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Blocking of FGFR signaling inhibits breast cancer cell proliferation through downregulation of D-type cyclins

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Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia.

21 January 2018

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Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo.

21 January 2018

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Control of developmental regulators by Polycomb in human embryonic stem cells

21 January 2018

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Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer

21 January 2018

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MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary

21 January 2018

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MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes

21 January 2018

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Genetic unmasking of an epigenetically silenced microRNA in human cancer cells

21 January 2018

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A microRNA DNA methylation signature for human cancer metastasis

21 January 2018

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Cell cycle, CDKs and cancer: a changing paradigm

21 January 2018

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A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

21 January 2018

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21 January 2018

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The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease

21 January 2018

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The fibroblast growth factor receptor inhibitor PD173074 blocks small cell lung cancer growth in vitro and in vivo.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08812.X

Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08812.X

Poor prognosis in acute lymphoblastic leukemia may relate to promoter hypermethylation of cancer-related genes

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08812.X

Epigenetic regulation of microRNAs in acute lymphoblastic leukemia

21 January 2018

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Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations

21 January 2018

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Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells

21 January 2018

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BCR-ABL-independent and RAS / MAPK pathway-dependent form of imatinib resistance in Ph-positive acute lymphoblastic leukemia cell line with activation of EphB4.

21 January 2018

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MiR-107 and MiR-185 can induce cell cycle arrest in human non small cell lung cancer cell lines.

21 January 2018

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miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A.

21 January 2018

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microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08812.X

10.1111/J.1365-2141.2011.08812.X

21 January 2018

Identifiers

DOI

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1 June 2018

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1 June 2018