(Q36871702)

16 August 2017

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title

Poor prognosis in acute lymphoblastic leukemia may relate to promoter hypermethylation of cancer-related genes (English)

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16 August 2017

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lymphoblastic leukemia

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7

Xabier Agirre

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author name string

Jose Roman-Gomez

1

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16 August 2017

Antonio Jimenez-Velasco

2

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16 August 2017

Manuel Barrios

3

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16 August 2017

Felipe Prosper

4

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16 August 2017

Anabel Heiniger

5

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16 August 2017

Antonio Torres

6

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16 August 2017

1 July 2007

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16 August 2017

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16 August 2017

48

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16 August 2017

7

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16 August 2017

1269-1282

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The power and the promise of DNA methylation markers

16 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

High sensitivity mapping of methylated cytosines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Folate, DNA methylation and colo-rectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Folic acid, polymorphism of methyl-group metabolism genes, and DNA methylation in relation to GI carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms and reduced risk of malignant lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Cancer epigenetics comes of age

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Epigenetics: regulation through repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Epigenetic gene silencing in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Gene silencing in cancer in association with promoter hypermethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

The history of cancer epigenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Histone acetylation and transcriptional regulatory mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Transcriptional coregulators in development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

DNA methylation, chromatin inheritance, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Histone deacetylase-dependent establishment and maintenance of broad low-level histone acetylation within a tissue-specific chromatin domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

DNMT cooperativity--the developing links between methylation, chromatin structure and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Dependence of transcriptional repression on CpG methylation density

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

5' CpG island hypermethylation is associated with transcriptional silencing of the p21(CIP1/WAF1/SDI1) gene and confers poor prognosis in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Abnormal methylation of the common PARK2 and PACRG promoter is associated with downregulation of gene expression in acute lymphoblastic leukemia and chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

ASPP1, a common activator of TP53, is inactivated by aberrant methylation of its promoter in acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Promoter hypermethylation of cancer-related genes: a strong independent prognostic factor in acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Lack of CpG island methylator phenotype defines a clinical subtype of T-cell acute lymphoblastic leukemia associated with good prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Concurrent methylation of multiple genes in childhood ALL: Correlation with phenotype and molecular subgroup.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

DNA methylation profiles of lymphoid and hematopoietic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Methylation of the asparagine synthetase promoter in human leukemic cell lines is associated with a specific methyl binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

The role of DNA hypermethylation in the pathogenesis and prognosis of acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Distinction of acute lymphoblastic leukemia from acute myeloid leukemia through microarray-based DNA methylation analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Epidemiologic considerations to assess altered DNA methylation from environmental exposures in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Presence of simian virus 40 DNA sequences in human lymphoid and hematopoietic malignancies and their relationship to aberrant promoter methylation of multiple genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Hypermethylation of the spleen tyrosine kinase promoter in T-lineage acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Prognosis in childhood and adult acute lymphoblastic leukaemia: a question of maturation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Identification of aberrantly methylated genes in association with adult T-cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Hypermethylation of death‐associated protein (DAP) kinase CpG island is frequent not only in B‐cell but also in T‐ and natural killer (NK)/T‐cell malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Methylation analysis of the adenomatous polyposis coli (APC) gene in adult T-cell leukemia/lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Epigenetic dysregulation of the Jak/STAT pathway by frequent aberrant methylation of SHP1 but not SOCS1 in acute leukaemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

DNA methylation in cancer: too much, but also too little

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Frequent hypomethylation in multiple promoter CpG islands is associated with global hypomethylation, but not with frequent promoter hypermethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Differential DNA hypermethylation and hypomethylation signatures in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Aberrant expression of the MEL1S gene identified in association with hypomethylation in adult T-cell leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Cellular differentiation, cytidine analogs and DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Epigenetic targets in hematopoietic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

DNA demethylation and cancer: therapeutic implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

DNA methylation as a therapeutic target in hematologic disorders: recent results in older patients with myelodysplasia and acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Hypermethylation and silencing of the putative tumor suppressor Tazarotene-induced gene 1 in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Preclinical evaluation of antineoplastic activity of inhibitors of DNA methylation (5-aza-2'-deoxycytidine) and histone deacetylation (trichostatin A, depsipeptide) in combination against myeloid leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Enhancement of antineoplastic action of 5-aza-2'-deoxycytidine by phenylbutyrate on L1210 leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Quercetin, a potent inhibitor against beta-catenin/Tcf signaling in SW480 colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

Inhibitors of DNA methylation: beyond myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701344899

10.1080/10428190701344899

21 January 2018

Identifiers

DOI

1 reference

16 August 2017

1 reference