(Q54584786)

1 June 2018

title

IDH1 and IDH2 mutations, immunohistochemistry and associations in a series of brain tumors. (English)

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1 June 2018

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Marta Mellai

1

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1 June 2018

Angela Piazzi

2

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1 June 2018

Valentina Caldera

3

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1 June 2018

Oriana Monzeglio

4

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1 June 2018

Paola Cassoni

5

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1 June 2018

Guido Valente

6

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1 June 2018

Davide Schiffer

7

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1 June 2018

publication date

4 June 2011

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1 June 2018

Journal of Neuro-Oncology

published in

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1 June 2018

volume

105

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1 June 2018

issue

2

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1 June 2018

page(s)

345-357

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1 June 2018

https://scigraph.springernature.com/pub.10.1007/s11060-011-0596-3

exact match

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cites work

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Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

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IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas

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IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas

21 January 2018

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IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

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Analysis of IDH1 and IDH2 mutations in Japanese glioma patients

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IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors

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IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders

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Mutations of IDH1 and IDH2 are not detected in brain metastases of colorectal cancer

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The next generation of glioma biomarkers: MGMT methylation, BRAF fusions and IDH1 mutations

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IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treatment of Cancer Brain Tumor Group

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All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2.

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Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network

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Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas.

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IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide

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IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas.

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Monoclonal antibody specific for IDH1 R132H mutation

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Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma.

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21 January 2018

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Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

21 January 2018

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Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas

21 January 2018

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Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis

21 January 2018

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Cyclin D1 expression in gliomas.

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Molecular signatures classify astrocytic gliomas by IDH1 mutation status.

21 January 2018

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12 December 2020

Chemical characterization of distinct subunits of pig heart DPN-specific isocitrate dehydrogenase.

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12 December 2020

High-throughput immunohistochemical profiling of primary brain tumors and non-neoplastic systemic organs with a specific antibody against the mutant isocitrate dehydrogenase 1 R132H protein.

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Probable assignment of soluble isocitrate dehydrogenase (IDH1) to 2q33.3.

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Isocitrate dehydrogenase 1/2 mutational analyses and 2-hydroxyglutarate measurements in Wilms tumors.

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12 December 2020

MGMT promoter hypermethylation in a series of 104 glioblastomas

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12 December 2020

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia

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12 December 2020

10.1007/S11060-011-0596-3

Identifiers

DOI

1 reference

1 June 2018

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1 June 2018