(Q54594283)

English

Loss of phosphatase and tensin homolog enhances cell invasion and migration through AKT/Sp-1 transcription factor/matrix metalloproteinase 2 activation in hepatocellular carcinoma and has clinicopathologic significance.

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21520171%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Loss of phosphatase and tensin homolog enhances cell invasion and migration through AKT/Sp-1 transcription factor/matrix metalloproteinase 2 activation in hepatocellular carcinoma and has clinicopathologic significance (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21520171%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

hepatocellular carcinoma

1 reference

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inferred from title

Irene Oi-lin Ng

6

1 reference

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29 January 2020

author name string

Karen Man-Fong Sze

1

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29 January 2020

Kris Lai-Ting Wong

2

1 reference

Europe PubMed Central

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29 January 2020

Glanice Kin-Yan Chu

3

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29 January 2020

Joyce Man-Fong Lee

4

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29 January 2020

Tai-On Yau

5

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29 January 2020

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1 May 2011

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29 January 2020

1 reference

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29 January 2020

53

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29 January 2020

1558-1569

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29 January 2020

5

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29 January 2020

Tenets of PTEN tumor suppression

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

PTEN/MMAC1 mutations in hepatocellular carcinomas.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Radiation-enhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3K/Akt/NF-kappaB signal transduction pathway.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

The hepatitis B virus X protein promotes hepatocellular carcinoma metastasis by upregulation of matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Establishment of cell lines from a primary hepatocellular carcinoma and its metastatis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

beta-Catenin mutation and overexpression in hepatocellular carcinoma: clinicopathologic and prognostic significance.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Sp1 is involved in Akt-mediated induction of VEGF expression through an HIF-1-independent mechanism.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Simultaneous loss of the DLC1 and PTEN tumor suppressors enhances breast cancer cell migration

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Regulation of PTEN by Rho small GTPases

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Skp2 overexpression increases the expression of MMP-2 and MMP-9 and invasion of lung cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

PRL1 promotes cell migration and invasion by increasing MMP2 and MMP9 expression through Src and ERK1/2 pathways

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Bcl-w promotes gastric cancer cell invasion by inducing matrix metalloproteinase-2 expression via phosphoinositide 3-kinase, Akt, and Sp1.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Membrane-type 1 matrix metalloproteinase is regulated by sp1 through the differential activation of AKT, JNK, and ERK pathways in human prostate tumor cells

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Sp1 and Sp3 transcription factors synergistically regulate HGF receptor gene expression in kidney

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Expression of PTEN, PPM1A and P-Smad2 in hepatocellular carcinomas and adjacent liver tissues

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Activation of PPARgamma increases PTEN expression in pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

PPARgamma activator rosiglitazone inhibits cell migration via upregulation of PTEN in human hepatocarcinoma cell line BEL-7404.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

21 January 2018

Molecular pathogenesis of hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

7 January 2021

based on heuristic

inferred from DOI database lookup

Treatment of hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression and significance of new tumor suppressor gene PTEN in primary liver cancer

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

7 January 2021

based on heuristic

inferred from DOI database lookup

Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/AKT pathways: involvement of invasive potential

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of PA/plasmin system in the processing of pro-MMP-9 and in the second step of pro-MMP-2 activation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

7 January 2021

based on heuristic

inferred from DOI database lookup

The alteration of PTEN tumor suppressor expression and its association with the histopathological features of human primary hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24232

7 January 2021

based on heuristic

inferred from DOI database lookup

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