(Q54594563)

1 June 2018

title

Klotho protein diminishes endothelial apoptosis and senescence via a mitogen-activated kinase pathway. (English)

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10

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author name string

Yoshihiro Maekawa

1

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Mitsuru Ohishi

2

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Masashi Ikushima

3

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Koichi Yamamoto

4

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Osamu Yasuda

5

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Ryosuke Oguro

6

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Hiroko Yamamoto-Hanasaki

7

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Yuji Tatara

8

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Yasushi Takeya

9

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publication date

26 April 2011

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Geriatrics and Gerontology International

published in

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volume

11

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issue

4

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page(s)

510-516

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Cellular and molecular mechanism of low-turnover osteopenia in the klotho-deficient mouse.

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Mutation of the mouse klotho gene leads to a syndrome resembling ageing

21 January 2018

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Disruption of klotho gene causes an abnormal energy homeostasis in mice

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Disruption of the klotho gene causes pulmonary emphysema in mice. Defect in maintenance of pulmonary integrity during postnatal life.

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Regulation of fibroblast growth factor-23 signaling by klotho

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Regulation of oxidative stress by the anti-aging hormone klotho

21 January 2018

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Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1447-0594.2011.00699.X

Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1447-0594.2011.00699.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-0594.2011.00699.X

Serine/threonine protein kinases and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-0594.2011.00699.X

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

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The complexity of PTEN: mutation, marker and potential target for therapeutic intervention

21 January 2018

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JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis

21 January 2018

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Efficient selection for high-expression transfectants with a novel eukaryotic vector

21 January 2018

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Oxidative stress decreases klotho expression in a mouse kidney cell line.

21 January 2018

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Iron accumulation during cellular senescence

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1447-0594.2011.00699.X

Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells.

21 January 2018

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Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway

21 January 2018

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Klotho protein deficiency and aging

21 January 2018

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Suppression of aging in mice by the hormone Klotho

21 January 2018

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Association of carotid atherosclerosis with genetic polymorphisms of the klotho gene in patients with hypertension

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1447-0594.2011.00699.X

Anti-apoptotic and anti-senescence effects of Klotho on vascular endothelial cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1447-0594.2011.00699.X

10.1111/J.1447-0594.2011.00699.X

21 January 2018

Identifiers

DOI

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1 June 2018

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1 June 2018