(Q54603551)

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Parthenolide sensitizes hepatocellular carcinoma cells to TRAIL by inducing the expression of death receptors through inhibition of STAT3 activation.

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25 January 2020

Parthenolide sensitizes hepatocellular carcinoma cells to TRAIL by inducing the expression of death receptors through inhibition of STAT3 activation (English)

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25 January 2020

hepatocellular carcinoma

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based on heuristic

inferred from title

Daniela Carlisi

1

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25 January 2020

Antonella D'Anneo

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25 January 2020

Giovanni Tesoriere

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Giovanni Tesoriere

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25 January 2020

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Renza Vento

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25 January 2020

Marianna Lauricella

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Marianna Lauricella

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25 January 2020

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Sonia Emanuele

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25 January 2020

Andrea Santulli

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Andrea Santulli

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25 January 2020

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Liliana Angileri

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25 January 2020

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1 June 2011

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25 January 2020

Journal of Cellular Physiology

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25 January 2020

226

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25 January 2020

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25 January 2020

1632-1641

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25 January 2020

NF-kappa B: ten years after

1 reference

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

1 reference

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TRAIL receptor-2 signals apoptosis through FADD and caspase-8

1 reference

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Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF-kappaB.

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STATs in oncogenesis

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21 January 2018

The histone deacetylase inhibitor suberoylanilide hydroxamic acid sensitises human hepatocellular carcinoma cells to TRAIL-induced apoptosis by TRAIL-DISC activation.

1 reference

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21 January 2018

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

1 reference

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21 January 2018

Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway

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Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

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21 January 2018

Differential responsiveness of human hepatoma cells versus normal hepatocytes to TRAIL in combination with either histone deacetylase inhibitors or conventional cytostatics

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SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor Bortezomib

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21 January 2018

Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.

1 reference

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21 January 2018

Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.

1 reference

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21 January 2018

Down-regulation of signal transducer and activator of transcription 3 expression using vector-based small interfering RNAs suppresses growth of human prostate tumor in vivo

1 reference

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21 January 2018

Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.22494

21 January 2018

The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells

1 reference

https://api.crossref.org/works/10.1002%2FJCP.22494

21 January 2018

STATs: signal transducers and activators of transcription

1 reference

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21 January 2018

Inhibition of ataxia telangiectasia mutated kinase activity enhances TRAIL-mediated apoptosis in human melanoma cells

1 reference

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21 January 2018

Susceptibility of cholangiocarcinoma cells to parthenolide-induced apoptosis

1 reference

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21 January 2018

Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: An integrated molecular profiling approach

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21 January 2018

Mitochondrial membrane permeabilization in cell death

1 reference

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21 January 2018

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

1 reference

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21 January 2018

Modes of p53 regulation

1 reference

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21 January 2018

Evidence that IL-6-type cytokine signaling in cardiomyocytes is inhibited by oxidative stress: parthenolide targets JAK1 activation by generating ROS

1 reference

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21 January 2018

Abrogation of constitutive STAT3 activity sensitizes human hepatoma cells to TRAIL-mediated apoptosis

1 reference

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21 January 2018

Parthenolide, a sesquiterpene lactone from the medical herb feverfew, shows anticancer activity against human melanoma cells in vitro.

1 reference

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21 January 2018

Knockdown of STAT3 expression by RNA interference inhibits the induction of breast tumors in immunocompetent mice

1 reference

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21 January 2018

p53 upregulates death receptor 4 expression through an intronic p53 binding site

1 reference

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21 January 2018

Dual role of the anti-inflammatory sesquiterpene lactone: regulation of life and death by parthenolide

1 reference

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21 January 2018

Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL

1 reference

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21 January 2018

Microtubule-interfering activity of parthenolide

1 reference

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Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase.

1 reference

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21 January 2018

Molecular basis of parthenolide-dependent proapoptotic activity in cancer cells.

1 reference

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21 January 2018

The synthetic cannabinoid WIN 55,212-2 sensitizes hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating p8/CCAAT/enhancer binding protein homologous protein (CHOP)/death rec

1 reference

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21 January 2018

Restoring chemotherapy and hormone therapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model

1 reference

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21 January 2018

Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

1 reference

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21 January 2018

Human hepatocellular carcinoma cells resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin.

1 reference

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21 January 2018

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

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21 January 2018

Antimyeloma effects of a sesquiterpene lactone parthenolide.

1 reference

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Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site.

1 reference

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21 January 2018

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

1 reference

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21 January 2018

Oxidative stress-mediated apoptosis. The anticancer effect of the sesquiterpene lactone parthenolide

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Identification and characterization of a new member of the TNF family that induces apoptosis

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The JAK kinases: not just another kinase drug discovery target

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Evaluation of combination chemotherapy: integration of nonlinear regression, curve shift, isobologram, and combination index analyses

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Identifiers

10.1002/JCP.22494

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21413021%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21413021%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

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