(Q54622561)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21204788%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure (English)

1 reference

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19 January 2020

5

1 reference

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19 January 2020

Claire Thornton

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21204788%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Nicola J Bright

2

1 reference

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19 January 2020

Magdalena Sastre

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21204788%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Phillip J Muckett

4

1 reference

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19 January 2020

language of work or name

English

0 references

publication date

1 March 2011

1 reference

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19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21204788%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

434

1 reference

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19 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21204788%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

503-512

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21204788%20AND%20SRC:MED&resulttype=core&format=json

Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice.

19 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

AMPK in Health and Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

5'-aminoimidazole-4-carboxamide riboside induces apoptosis in human neuroblastoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Phospho-dependent functional modulation of GABA(B) receptors by the metabolic sensor AMP-dependent protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Neuroprotective effects of adenosine monophosphate-activated protein kinase inhibition and gene deletion in stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Drosophila alicorn is a neuronal maintenance factor protecting against activity-induced retinal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Activation of PAR-1 kinase and stimulation of tau phosphorylation by diverse signals require the tumor suppressor protein LKB1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Long-term culture of mouse cortical neurons as a model for neuronal development, aging, and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Mammalian AMP-activated protein kinase: functional, heterotrimeric complexes by co-expression of subunits in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Amyloid beta peptide induces tau phosphorylation and loss of cholinergic neurons in rat primary septal cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Mammalian SAD kinases are required for neuronal polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Muscarinic receptor activation of AMP-activated protein kinase inhibits orexigenic neuropeptide mRNA expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Amyloid beta oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Glutamate and neurotrophic factors in neuronal plasticity and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Memantine in moderate-to-severe Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Memantine protects rat cortical cultured neurons against beta-amyloid-induced toxicity by attenuating tau phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Glycogen synthase kinase 3beta phosphorylates tau at both primed and unprimed sites. Differential impact on microtubule binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Beta-amyloid1-42 gene transfer model exhibits intraneuronal amyloid, gliosis, tau phosphorylation, and neuronal loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Role of serine/threonine protein phosphatase in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Beta-amyloid-induced neuronal apoptosis involves c-Jun N-terminal kinase-dependent downregulation of Bcl-w.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

Disturbed cross talk between insulin-like growth factor I and AMP-activated protein kinase as a possible cause of vascular dysfunction in the amyloid precursor protein/presenilin 2 mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

The role of tau in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101485

21 January 2018

Identifiers

DOI

10.1042/BJ20101485

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21204788%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference