(Q54809015)

English

CCRF-CEM

cell line

CCRF/CEM
CCRFCEM
CCRF.CEM
CCRF CEM
CCRF
CEM
CEM-CCRF
CEM-CCRF (CAMR)
CCRF/CEM/0
CEM/0
CEM-0
CCRF-CEM/S
GM03671
GM03671C

In more languages

Statements

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cancer cell line

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described by source

Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines

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Constitutive production of B cell differentiation factor-like activity by human T and B cell lines.

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Morphologic variations in human leukemic lymphoblasts (CCRF-CEM cells) after long-term culture and exposure to chemotherapeutic agents:A study with the electron microscope

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Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies

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Growth of human malignant lymphoid cell lines in serum-free medium

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Homozygous deletions of the CDKN2 (MTS1/p16ink4) gene in cell lines established from children with acute lymphoblastic leukemia.

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Overexpression of the MDM2 gene by childhood acute lymphoblastic leukemia cells expressing the wild-type p53 gene.

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Interferon system defects in malignant T-cells.

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Homozygous loss of the MTS1/p16 and MTS2/p15 genes in lymphoma and lymphoblastic leukaemia cell lines

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p16INK4/p15INK4B gene inactivation is a frequent event in malignant T-cell lines.

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Expression and regulation of Bcl-2, Bcl-xl, and Bax correlate with p53 status and sensitivity to apoptosis in childhood acute lymphoblastic leukemia

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Screening the p53 status of human cell lines using a yeast functional assay

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Use of the comet test in the evaluation of multidrug resistance of human cell lines

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Telomere analysis by fluorescence in situ hybridization and flow cytometry

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Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia

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Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression.

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Heterogeneity of T-acute lymphoblastic leukemia (T-ALL) cell lines: suggestion for classification by immunophenotype and T-cell receptor studies

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Alterations of the p53, p21, p16, p15 and RAS genes in childhood T-cell acute lymphoblastic leukemia

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Systematic variation in gene expression patterns in human cancer cell lines

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CONTINUOUS CULTURE OF HUMAN LYMPHOBLASTS FROM PERIPHERAL BLOOD OF A CHILD WITH ACUTE LEUKEMIA.

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JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders

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Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

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Authenticity and drug resistance in a panel of acute lymphoblastic leukaemia cell lines

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DNA fingerprinting of the NCI-60 cell line panel

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A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers

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National Cancer Institute pediatric preclinical testing program: model description for in vitro cytotoxicity testing

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Identification of cancer cell-line origins using fluorescence image-based phenomic screening

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High accuracy mutation detection in leukemia on a selected panel of cancer genes

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Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation

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The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology

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Global proteome analysis of the NCI-60 cell line panel

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The metabolic demands of cancer cells are coupled to their size and protein synthesis rates

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High resolution copy number variation data in the NCI-60 cancer cell lines from whole genome microarrays accessible through CellMiner

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Long non-coding RNA expression profiling in the NCI60 cancer cell line panel using high-throughput RT-qPCR

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A landscape of pharmacogenomic interactions in cancer.

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A map of mobile DNA insertions in the NCI-60 human cancer cell panel.

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Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

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Evaluation of NCI-7 Cell Line Panel as a Reference Material for Clinical Proteomics.

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Expression of leukocyte common antigen (CD45) on various human leukemia/lymphoma cell lines

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Frequent mutations in the p53 tumor suppressor gene in human leukemia T-cell lines

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Disruption of the human SCL locus by "illegitimate" V-(D)-J recombinase activity

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Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay

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Type C virus particles produced in human T-cell lines derived from acute lymphoblastic leukemia and a leukemic T-lymphoid malignancy

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Frameshift mutations of the hMSH6 gene in human leukemia cell lines.

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Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

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The cardiac homeobox gene NKX2-5 is deregulated by juxtaposition with BCL11B in pediatric T-ALL cell lines via a novel t(5;14)(q35.1;q32.2)

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

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HLA class I and II genotype of the NCI-60 cell lines

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Human T-cell lines with well-defined T-cell receptor gene rearrangements as controls for the BIOMED-2 multiplex polymerase chain reaction tubes.

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Signatures of mutation and selection in the cancer genome

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An Interactive Resource to Probe Genetic Diversity and Estimated Ancestry in Cancer Cell Lines

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The LL-100 panel: 100 cell lines for blood cancer studies.

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The Protein Profile of the Human Immature T-cell Line CCRF-CEM

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Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance

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Differential expression of the amv gene in human hematopoietic cells

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PTEN gene alterations in lymphoid neoplasms

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Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines

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Cytosine arabinoside (ara-C) resistance confers cross-resistance or collateral sensitivity to other classes of anti-leukemic drugs

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Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000), 255-262

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Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 3'-BCL11B enhancers and coregulation by PU.1 and HMGA1.

1 reference

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Reduced drug incorporation into DNA and antiapoptosis as the crucial mechanisms of resistance in a novel nelarabine-resistant cell line

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The animal cell culture collection

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Detection of T-cell lymphoma-associated antigens on cord blood lymphocytes and phytohemagglutinin-stimulated blasts

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Isoenzyme studies in human leukemia-lymphoma cell lines--1. Carboxylic esterase

1 reference

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Isoenzyme studies in human leukemia-lymphoma cell lines--III. beta-Hexosaminidase (E.C. 3.2.1.30).

1 reference

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Isoenzyme studies in human leukemia-lymphoma cells lines--II. Acid phosphatase

1 reference

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Epstein-barr virus-negative human malignant T-cell lines

1 reference

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Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines

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established from medical condition

T-cell childhood acute lymphocytic leukemia

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derived from organism type

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http://purl.obolibrary.org/obo/BTO_0000736

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http://purl.obolibrary.org/obo/EFO_0002128

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http://purl.obolibrary.org/obo/CLO_0002334

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http://purl.obolibrary.org/obo/CLO_0015478

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http://purl.obolibrary.org/obo/CLO_0050143

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Identifiers

Cell Line Ontology ID

1 reference

Cellosaurus release 44

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1 reference

Cellosaurus release 44

7 January 2023

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Cellosaurus release 44

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Google Knowledge Graph ID

0 references

Sitelinks

Wikipedia(1 entry)

zhwiki CCRF-CEM

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